# Computational tools help improve protein stability but with a solubility tradeoff

> Research article (Journal of Biological Chemistry, 2017) · cited 120× · AI/ML

**Wikidata**: [openalex:W2734861826](https://www.wikidata.org/wiki/openalex:W2734861826)  
**Source**: https://4ort.xyz/entity/computational-tools-help-improve-protein-stability-but-with-a-solubility-tradeoff