# common variable immunodeficiency

> immune disorder

**Wikidata**: [Q1472818](https://www.wikidata.org/wiki/Q1472818)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Common_variable_immunodeficiency)  
**Source**: https://4ort.xyz/entity/common-variable-immunodeficiency


## References

1. Disease Ontology
2. Freebase Data Dumps. 2013
3. [Source](http://www.patient.co.uk/patientplus/c.htm)
4. Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.
5. TACI is mutant in common variable immunodeficiency and IgA deficiency
6. Genetic CD21 deficiency is associated with hypogammaglobulinemia
7. Early-onset inflammatory bowel disease and common variable immunodeficiency-like disease caused by IL-21 deficiency
8. B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans.
9. CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency
10. Germline mutations in NFKB2 implicate the noncanonical NF-κB pathway in the pathogenesis of common variable immunodeficiency
11. An antibody-deficiency syndrome due to mutations in the CD19 gene
12. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
13. Deleterious mutations in LRBA are associated with a syndrome of immune deficiency and autoimmunity
14. CD20 deficiency in humans results in impaired T cell-independent antibody responses
15. [Identifiers.org](https://registry.identifiers.org/registry/doid)
16. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)