# Collagen type IV alpha 1 chain

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21130061](https://www.wikidata.org/wiki/Q21130061)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Collagen,_type_IV,_alpha_1)  
**Source**: https://4ort.xyz/entity/collagen-type-iv-alpha-1-chain


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2095222)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P02462)
4. Q20641742
5. [Novel mutations in three families confirm a major role of COL4A1 in hereditary porencephaly](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
6. [Novel COL4A1 mutations associated with HANAC syndrome: A role for the triple helical CB3[IV] domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
8. [The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
9. [Type I, II, III, IV, V, and VI collagens serve as extracellular ligands for the isoforms of platelet-derived growth factor (AA, BB, and AB)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
10. [Novel COL4A1 mutations associated with HANAC syndrome: A role for the triple helical CB3[IV] domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
13. [Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
14. [Comprehensive proteomic characterization of stem cell-derived extracellular matrices](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
15. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
16. [Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
17. [SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
18. [Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
19. [Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
20. [Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
21. [SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
22. [Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
23. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
24. [Comprehensive proteomic characterization of stem cell-derived extracellular matrices](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
25. [Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
26. [Novel mutations in three families confirm a major role of COL4A1 in hereditary porencephaly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
27. [Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
28. [Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02462&geneProductId=UniProtKB:P02462)
29. [The human plasma proteome: a nonredundant list developed by combination of four separate sources](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
30. [Novel COL4A1 mutations cause cerebral small vessel disease by haploinsufficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
31. [Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
32. [Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
33. [COL4A1 mutations and hereditary angiopathy, nephropathy, aneurysms, and muscle cramps](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
34. [Cerebrovascular disease related to COL4A1 mutations in HANAC syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02462)
35. ensembl Release 93