# Collagen, type II, alpha 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14877688](https://www.wikidata.org/wiki/Q14877688)  
**Source**: https://4ort.xyz/entity/collagen-type-ii-alpha-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P28481)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
6. [Disruption of the developmentally-regulated Col2a1 pre-mRNA alternative splicing switch in a transgenic knock-in mouse model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
8. [Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
9. [Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
10. [Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
11. [Disproportionate micromelia (Dmm): an incomplete dominant mouse dwarfism with abnormal cartilage matrix](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
12. [Expression and localization of collagen-binding stress protein Hsp47 in mouse embryo development: comparison with types I and II collagen](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
13. [Age-dependent changes in the expression of matrix components in the mouse eye](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
14. [Protein consequences of the Col2a1 C-propeptide mutation in the chondrodysplastic Dmm mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
15. [Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
16. [Protein consequences of the Col2a1 C-propeptide mutation in the chondrodysplastic Dmm mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
17. [Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
18. [Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
19. [Sox9 plays multiple roles in the lung epithelium during branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
20. [The transient expression of type II collagen at tissue interfaces during mammalian craniofacial development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
21. [Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
22. [Collagen XXVII organises the pericellular matrix in the growth plate](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
23. [Immunohistochemistry of collagen types II and X, and enzyme‐histochemistry of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
24. [Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
25. [Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
26. [Disproportionate micromelia (Dmm): an incomplete dominant mouse dwarfism with abnormal cartilage matrix](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
27. [Expression and localization of collagen-binding stress protein Hsp47 in mouse embryo development: comparison with types I and II collagen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
28. [Sox9 plays multiple roles in the lung epithelium during branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
29. [Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
30. [Dentin Sialophosphoprotein (DSPP) Plays an Essential Role in the Postnatal Development and Maintenance of Mouse Mandibular Condylar Cartilage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
31. [Immunohistochemistry of collagen types II and X, and enzyme‐histochemistry of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
32. [The transient expression of type II collagen at tissue interfaces during mammalian craniofacial development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
33. [Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
34. [Collagen XXVII organises the pericellular matrix in the growth plate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
35. [The role of collagen II and cartilage fibril-associated molecules in skeletal development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
36. [Skeletal development in transgenic mice expressing a mutation at Gly574Ser of type II collagen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
37. [Disproportionate micromelia (Dmm) in mice caused by a mutation in the C-propeptide coding region of Col2a1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
38. [Craniofacial and otic capsule abnormalities in a transgenic mouse strain with a Col2a1 mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
39. [The transcription factor Znf219 regulates chondrocyte differentiation by assembling a transcription factory with Sox9](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
40. [Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
41. [SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
42. [Restoration of normal bone development by human homologue of collagen type II (COL2A1) gene in Col2a1 null mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
43. [Skeletal development in transgenic mice expressing a mutation at Gly574Ser of type II collagen](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
44. [Disproportionate micromelia (Dmm) in mice caused by a mutation in the C-propeptide coding region of Col2a1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
45. [Inactivation of one allele of the type II collagen gene alters the collagen network in murine articular cartilage and makes cartilage softer](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
46. [Collagen II is essential for the removal of the notochord and the formation of intervertebral discs](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
47. [Histochemical, immunofluorescence, and ultrastructural differences in fetal cartilage among three genetically distinct chondrodystrophic mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
48. [Transgenic mice with targeted inactivation of the Col2 alpha 1 gene for collagen II develop a skeleton with membranous and periosteal bone but no endochondral bone](http://www.ebi.ac.uk/QuickGO/annotations?protein=P28481&geneProductId=UniProtKB:P28481)
49. [Pulmonary hypoplasia associated with reduced thoracic space in mice with disproportionate micromelia (DMM)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)
50. [Restoration of normal bone development by human homologue of collagen type II (COL2A1) gene in Col2a1 null mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28481)