# Cold Spring Harbor Laboratory

> private, non-profit research institution in New York, United States

**Wikidata**: [Q609768](https://www.wikidata.org/wiki/Q609768)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Cold_Spring_Harbor_Laboratory)  
**Source**: https://4ort.xyz/entity/cold-spring-harbor-laboratory

## Summary
Cold Spring Harbor Laboratory is a private, non-profit research institution in New York, United States, founded in 1890. It specializes in biological research, education, and publishing, housing the Watson School of Biological Sciences and hosting affiliated researchers in genetics and bioinformatics.

## Key Facts
- Founded in 1890, with legal designation as a 501(c)(3) organization
- Located in Laurel Hollow, New York, covering 100 acres (coordinates: 40.861944, -73.467222)
- Short name: CSHL; aliases include Cold Spring Harbor Laboratories and international variants
- Operates the graduate school Watson School of Biological Sciences (established 1998)
- Owns bioRxiv, a preprint server for biology research
- Annual revenue exceeded $257 million USD in 2023, with total assets of $1.24 billion USD
- Affiliated with notable researchers including Yaniv Erlich, Adam C. Siepel, and Michael C. Schatz
- Listed on the National Register of Historic Places since 1994 as the Cold Spring Harbor Laboratory Historic District

## FAQs
### Q: What is Cold Spring Harbor Laboratory primarily known for?
A: It is a private, non-profit research institution focusing on biological sciences, genetics, and bioinformatics. It operates a graduate school and hosts advanced research programs while maintaining historical significance in molecular biology.

### Q: Who are some notable researchers affiliated with Cold Spring Harbor Laboratory?
A: Affiliated researchers include Yaniv Erlich (computer scientist), Adam C. Siepel (bioinformatician and geneticist), Michael C. Schatz (computer scientist and bioinformatician), and Ken Youens-Clark (researcher, engineer, and programmer).

### Q: When was Cold Spring Harbor Laboratory established?
A: It was founded in 1890, with its graduate school, the Watson School of Biological Sciences, established in 1998.

### Q: What financial scale does Cold Spring Harbor Laboratory operate at?
A: In 2023, its revenue reached $257,960,426 USD with total assets of $1,242,678,094 USD, supported by donations of $189,445,361 USD that year.

## Why It Matters
Cold Spring Harbor Laboratory represents a cornerstone of modern biological research and education. Its historic contributions to molecular biology, coupled with its current leadership in genomics and computational biology, advance scientific understanding of genetic mechanisms and disease. As a nonprofit, it combines academic rigor with practical applications—evidenced by its operation of bioRxiv and partnerships with institutions like the New York Genome Center. Its dual role as both a research powerhouse and educator (via the Watson School) shapes the next generation of scientists while preserving its legacy as a National Historic District.

## Notable For
- Historic preservation: Recognized as a National Register of Historic Places district since 1994
- Scientific publishing: Owns and operates bioRxiv, a leading biology preprint server
- Financial scale: Maintains billion-dollar asset totals and multi-million-dollar annual donations/revenue
- Educational leadership: Houses the Watson School of Biological Sciences, offering graduate education since 1998
- Research ecosystem: Affiliated with pioneering researchers in computational genetics and bioinformatics

## Body
### Overview
Cold Spring Harbor Laboratory (CSHL) is a private, non-profit research institution based in Laurel Hollow, New York. It occupies a 100-acre campus and functions as a research institute, academic publisher, and nonprofit organization. Founded in 1890, it became a 501(c)(3) organization and maintains the Watson School of Biological Sciences as its graduate education arm.

### Affiliations
- Researchers: Affiliated with computational biologists Yaniv Erlich (b. 1979), Adam C. Siepel (bioinformatician/geneticist, b. 1972), and Michael C. Schatz (bioinformatician)
- Institutions: Member of the New York Genome Center, Association of Independent Research Institutes, and Council on Governmental Relations
- Ownership: Operates bioRxiv, a biology preprint server

### Financials
- Revenue: Ranged from $134.4M (2013) to $307.6M (2019), peaking at $257.96M in 2023
- Assets: Exceeded $1.24B in 2023, growing from $660.5M (2011)
- Donations: Varied from $95.46M (2015) to $189.45M (2023), with $164.33M in 2019

### Location & Recognition
- Situated in Laurel Hollow, New York (coordinates: 40.861944°N, 73.467222°W)
- Listed on the National Register of Historic Places (1994) as the Cold Spring Harbor Laboratory Historic District
- Maintains multiple social media handles: Twitter (@CSHL), Facebook (cshlnews), Instagram (cshlnews)

### Identifiers
- ISNI: 0000000403873667
- ROR ID: 02qz8b764
- GRID ID: grid.225279.9
- Website: https://www.cshl.edu/ (English-language)

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## References

1. GRID Release 2017-01-10
2. Virtual International Authority File
3. BnF authorities
4. CiNii Research
5. [Source](https://www.nygenome.org/about-us/member-institutions/)
6. [Source](https://www.cogr.edu/cogr-membership-list)
7. [Source](https://airi.org/Institutional_Members)
8. Between biochemistry, physics, and politics. Characteristics of molecular biology in the USSR (1930s–1960s)
9. Freebase Data Dumps. 2013
10. Czech National Authority Database
11. MusicBrainz
12. National Register of Historic Places
13. [Source](https://www.charitynavigator.org/ein/112013303)
14. GeoNames
15. [Source](https://n2t.net/e/pub/naan_registry.txt)
16. Google Knowledge Graph
17. Nonprofit Explorer
18. [Nonprofit Explorer](https://projects.propublica.org/nonprofits/organizations/112013303)
19. GRID Release 2015-12-14
20. GRID Release 2016-12-06
21. Quora
22. Aligned ISNI and Ringgold identifiers for institutions
23. [Source](https://www.cshl.edu/)
24. [Source](https://www.charitynavigator.org/index.cfm?bay=search.alpha)
25. Microsoft Academic Knowledge Graph
26. [Source](https://www.charitynavigator.org/index.cfm?bay=search.summary&orgid=3529&oldpage)
27. National Library of Israel Names and Subjects Authority File