# Closed loop control of lactate concentration in mammalian cell culture by Raman spectroscopy leads to improved cell density, viability, and biopharmaceutical protein production

> Research article (Biotechnology and Bioengineering, 2016) · cited 100× · AI/ML

**Wikidata**: [openalex:W2399070630](https://www.wikidata.org/wiki/openalex:W2399070630)  
**Source**: https://4ort.xyz/entity/closed-loop-control-of-lactate-concentration-in-mammalian-cell-culture-by-raman-spectroscopy-leads-to-improved-cell-dens