# Clock circadian regulator

> mammalian protein found in Homo sapiens

**Wikidata**: [Q3610562](https://www.wikidata.org/wiki/Q3610562)  
**Source**: https://4ort.xyz/entity/clock-circadian-regulator


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15516)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
5. [Regulation of clock and NPAS2 DNA binding by the redox state of NAD cofactors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
6. [Molecular cloning and characterization of the human CLOCK gene: expression in the suprachiasmatic nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
7. [CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
8. [Peripheral CLOCK regulates target-tissue glucocorticoid receptor transcriptional activity in a circadian fashion in man](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
9. [DEC1 modulates the circadian phase of clock gene expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15516&geneProductId=UniProtKB:O15516)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15516&geneProductId=UniProtKB:O15516)
11. [p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
12. [DEC1 modulates the circadian phase of clock gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
13. [Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
14. [Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
15. [Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
16. [Histone acetyltransferase-dependent chromatin remodeling and the vascular clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
17. [The transcriptional repressor ID2 can interact with the canonical clock components CLOCK and BMAL1 and mediate inhibitory effects on mPer1 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
18. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15516&geneProductId=UniProtKB:O15516)
19. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
20. [The basic-helix-loop-helix-PAS orphan MOP3 forms transcriptionally active complexes with circadian and hypoxia factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
21. [A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
22. [A meeting of two chronobiological systems: circadian proteins Period1 and BMAL1 modulate the human hair cycle clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15516)
23. Ensembl Release 99
24. UMLS 2023