# Class II major histocompatibility complex transactivator

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5011707](https://www.wikidata.org/wiki/Q5011707)  
**Source**: https://4ort.xyz/entity/class-ii-major-histocompatibility-complex-transactivator


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P33076)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
5. [CATERPILLER: a novel gene family important in immunity, cell death, and diseases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
6. [Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
7. [ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
8. [PML promotes MHC class II gene expression by stabilizing the class II transactivator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
9. [The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
10. [SIRT1 links CIITA deacetylation to MHC II activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
11. [The class II trans-activator CIITA interacts with the TBP-associated factor TAFII32](http://www.ebi.ac.uk/QuickGO/annotations?protein=P33076&geneProductId=UniProtKB:P33076)
12. [HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
13. [A quantitative study of the glia of the Purkinje cell layer of the cerebellum in mammals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P33076&geneProductId=UniProtKB:P33076)
15. [Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
16. [NLR family member NLRC5 is a transcriptional regulator of MHC class I genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P33076&geneProductId=UniProtKB:P33076)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
18. [NLR family member NLRC5 is a transcriptional regulator of MHC class I genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
19. [The class II trans-activator CIITA interacts with the TBP-associated factor TAFII32](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P33076)
20. Ensembl Release 99
21. Identifiers.org