# chronic granulomatous disease

> diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds used to kill certain ingested pathogens

**Wikidata**: [Q2165663](https://www.wikidata.org/wiki/Q2165663)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Chronic_granulomatous_disease)  
**Source**: https://4ort.xyz/entity/chronic-granulomatous-disease


## References

1. Disease Ontology
2. Monarch Disease Ontology release 2018-06-29
3. [Source](http://www.patient.co.uk/patientplus/c.htm)
4. Drug Indications Extracted from FAERS
5. Genetic variants of chronic granulomatous disease: prevalence of deficiencies of two cytosolic components of the NADPH oxidase system
6. A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity.
7. A missense mutation in the neutrophil cytochrome b heavy chain in cytochrome-positive X-linked chronic granulomatous disease
8. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000165168/MONDO_0018305)
9. Human neutrophil cytochrome b light chain (p22-phox). Gene structure, chromosomal location, and mutations in cytochrome-negative autosomal recessive chronic granulomatous disease
10. [Identifiers.org](https://registry.identifiers.org/registry/doid)
11. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)