# Chromobox 5

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21112513](https://www.wikidata.org/wiki/Q21112513)  
**Source**: https://4ort.xyz/entity/chromobox-5-q21112513


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P45973)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
5. [Human BAHD1 promotes heterochromatic gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
6. [INCENP Centromere and Spindle Targeting: Identification of Essential Conserved Motifs and Involvement of Heterochromatin Protein HP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
7. [Physical and Functional Interaction between Heterochromatin Protein 1α and the RNA-binding Protein Heterogeneous Nuclear Ribonucleoprotein U](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
8. [A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
9. [Quantitative Interaction Proteomics and Genome-wide Profiling of Epigenetic Histone Marks and Their Readers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
10. [Chromatin components as part of a putative transcriptional repressing complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
11. [Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
12. [WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
13. [The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
14. [The deSUMOylase SENP7 promotes chromatin relaxation for homologous recombination DNA repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
15. [Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
16. [Analysis of the human HP1 interactome reveals novel binding partners](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
17. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
18. [SET‐domain bacterial effectors target heterochromatin protein 1 to activate host rDNA transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
19. [The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
20. [Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
21. [Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
22. [A High-Density Map for Navigating the Human Polycomb Complexome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
23. [Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
24. [KAP-1 corepressor protein interacts and colocalizes with heterochromatic and euchromatic HP1 proteins: a potential role for Krüppel-associated box-zinc finger proteins in heterochromatin-mediated gene silencing.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
25. [A directed protein interaction network for investigating intracellular signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
26. [Cell cycle-dependent phosphorylation of the ATRX protein correlates with changes in nuclear matrix and chromatin association](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
27. [Heterochromatin links to centromeric protection by recruiting shugoshin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
28. [Tudor, MBT and chromo domains gauge the degree of lysine methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
29. [Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
30. [Human POGZ modulates dissociation of HP1α from mitotic chromosome arms through Aurora B activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
31. [Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
32. [Pooled-matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
33. [A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
34. [The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
35. [Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
36. [JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
37. [Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45973)
38. Ensembl Release 99
39. UMLS 2023