# Chromobox 4

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109155](https://www.wikidata.org/wiki/Q21109155)  
**Source**: https://4ort.xyz/entity/chromobox-4-q21109155


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00257)
3. Q20641742
4. [The SUMO E3 Ligase Activity of Pc2 Is Coordinated through a SUMO Interaction Motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
5. [A Role for Non-Covalent SUMO Interaction Motifs in Pc2/CBX4 E3 Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
6. [The Polycomb Protein Pc2 Is a SUMO E3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
7. [Interference with the Expression of a Novel Human Polycomb Protein, hPc2, Results in Cellular Transformation and Apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
9. [SUMO5, a Novel Poly-SUMO Isoform, Regulates PML Nuclear Bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
10. [DNA methyltransferase 3B acts as a co-repressor of the human polycomb protein hPc2 to repress fibroblast growth factor receptor 3 transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
11. [A Human Protein-Protein Interaction Network: A Resource for Annotating the Proteome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
12. [ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
13. [A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
14. [A High-Density Map for Navigating the Human Polycomb Complexome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
15. [Ubiquitin‐specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
16. [Cbx4 Governs HIF-1α to Potentiate Angiogenesis of Hepatocellular Carcinoma by Its SUMO E3 Ligase Activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
17. [Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
18. [Several Distinct Polycomb Complexes Regulate and Co-Localize on the INK4a Tumor Suppressor Locus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
19. [Human Cystathionine β-Synthase Is a Target for Sumoylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
20. [The Core of the Polycomb Repressive Complex Is Compositionally and Functionally Conserved in Flies and Humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
21. [Interaction Proteomics Analysis of Polycomb Proteins Defines Distinct PRC1 Complexes in Mammalian Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
22. [MPc2 , a new murine homolog of the Drosophila polycomb protein is a member of the mouse polycomb transcriptional repressor complex 1 1Edited by M. Yaniv](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00257)
23. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00257&geneProductId=UniProtKB:O00257)
24. Ensembl Release 99