# Cholinergic receptor, nicotinic, alpha polypeptide 4

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981633](https://www.wikidata.org/wiki/Q21981633)  
**Source**: https://4ort.xyz/entity/cholinergic-receptor-nicotinic-alpha-polypeptide-4


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O70174)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
5. [The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
7. [Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
8. [A role for LYNX2 in anxiety-related behavior](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
9. [Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
10. [UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
11. [Mechanisms of Inhibition and Potentiation of α4β2 Nicotinic Acetylcholine Receptors by Members of the Ly6 Protein Family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
12. [Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
13. [A polymorphism in the mouse neuronal alpha4 nicotinic receptor subunit results in an alteration in receptor function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
14. [Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
15. [Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
16. [Exocytic trafficking is required for nicotine-induced up-regulation of alpha 4 beta 2 nicotinic acetylcholine receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
17. [Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
19. [The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
20. [Postnatal upregulation of alpha4 and alpha3 nicotinic receptor subunits in the brain of alpha7 nicotinic receptor-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
21. [Mechanisms of Inhibition and Potentiation of α4β2 Nicotinic Acetylcholine Receptors by Members of the Ly6 Protein Family](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
22. [Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
23. [Nicotinic receptors regulate B lymphocyte activation and immune response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
24. [Postnatal upregulation of alpha4 and alpha3 nicotinic receptor subunits in the brain of alpha7 nicotinic receptor-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
25. [Acute Ethanol Administration Upregulates Synaptic α4-Subunit of Neuronal Nicotinic Acetylcholine Receptors within the Nucleus Accumbens and Amygdala.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
26. [Subsynaptic localization of nicotinic acetylcholine receptor subunits: a comparative study in the mouse and rat striatum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
27. [Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
28. [Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
29. [Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
30. [Reduced antinociception in mice lacking neuronal nicotinic receptor subunits](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
31. [Exocytic trafficking is required for nicotine-induced up-regulation of alpha 4 beta 2 nicotinic acetylcholine receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
32. [Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy.](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
33. [Cholinergic chemosensory cells in the trachea regulate breathing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
34. [Reduced antinociception in mice lacking neuronal nicotinic receptor subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70174)
35. [Point mutant mice with hypersensitive alpha 4 nicotinic receptors show dopaminergic deficits and increased anxiety.](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
36. [Novel modulation of neuronal nicotinic acetylcholine receptors by association with the endogenous prototoxin lynx1](http://www.ebi.ac.uk/QuickGO/annotations?protein=O70174&geneProductId=UniProtKB:O70174)
37. ensembl Release 106