# Checkpoint kinase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21495077](https://www.wikidata.org/wiki/Q21495077)  
**Source**: https://4ort.xyz/entity/checkpoint-kinase-1-q21495077


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O35280)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
5. [Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35280&geneProductId=UniProtKB:O35280)
7. [Mammalian TIMELESS Is Involved in Period Determination and DNA Damage-Dependent Phase Advancing of the Circadian Clock](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
8. [Chk1 is a histone H3 threonine 11 kinase that regulates DNA damage-induced transcriptional repression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
10. [Large-scale identification of mammalian proteins localized to nuclear sub-compartments](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35280&geneProductId=UniProtKB:O35280)
11. [Large-scale identification of mammalian proteins localized to nuclear sub-compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
12. [Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
13. [Hus1 Acts Upstream of Chk1 in a Mammalian DNA Damage Response Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
14. [VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
15. [Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
16. [Aberrant cell cycle checkpoint function and early embryonic death in Chk1(-/-) mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35280)
17. [Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest](http://www.ebi.ac.uk/QuickGO/annotations?protein=O35280&geneProductId=UniProtKB:O35280)
18. ensembl Release 106