# Ceramide synthase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21173451](https://www.wikidata.org/wiki/Q21173451)  
**Source**: https://4ort.xyz/entity/ceramide-synthase-1-q21173451


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P27544)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
7. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
8. [Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
9. [(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
10. [Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
11. [(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
12. [Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
13. [Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
14. [Mechanisms of ceramide-mediated repression of the human telomerase reverse transcriptase promoter via deacetylation of Sp3 by histone deacetylase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
15. [Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
16. [2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
17. [Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
18. [Mammalian Lass6 and its related family members regulate synthesis of specific ceramides](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
19. [Mechanisms of ceramide-mediated repression of the human telomerase reverse transcriptase promoter via deacetylation of Sp3 by histone deacetylase 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P27544&geneProductId=UniProtKB:P27544)
20. [2-Hydroxy-ceramide synthesis by ceramide synthase family: enzymatic basis for the preference of FA chain length](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
21. [Mammalian Lass6 and its related family members regulate synthesis of specific ceramides](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P27544)
22. Ensembl Release 99