# Centrosomal protein 290

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21117111](https://www.wikidata.org/wiki/Q21117111)  
**Source**: https://4ort.xyz/entity/centrosomal-protein-290-q21117111


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15078)
3. Q20641742
4. [The centriolar satellite protein CCDC66 interacts with CEP290 and functions in cilium formation and trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
5. [CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
6. [The centriolar satellite protein AZI1 interacts with BBS4 and regulates ciliary trafficking of the BBSome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
7. [The centriolar satellite protein Cep131 is important for genome stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
8. [Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
9. [Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
10. [Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
11. [CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficient in human ciliary disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
12. [Genetic and physical interaction between the NPHP5 and NPHP6 gene products](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
13. [Centriolar kinesin Kif24 interacts with CP110 to remodel microtubules and regulate ciliogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
14. [Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
15. [Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
16. [CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
17. [Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
18. [A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
19. [The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
20. [BBS mutations modify phenotypic expression of CEP290-related ciliopathies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
21. [Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
23. [Proteomic characterization of the human centrosome by protein correlation profiling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
24. [Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
25. [Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
26. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15078&geneProductId=UniProtKB:O15078)
27. [A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
28. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
29. [The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
30. [Mutations in human homologue of chickentalpid3gene (KIAA0586) cause a hybrid ciliopathy with overlapping features of Jeune and Joubert syndromes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15078)
31. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15078&geneProductId=UniProtKB:O15078)
32. Ensembl Release 99