# Centromere protein A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21109722](https://www.wikidata.org/wiki/Q21109722)  
**Source**: https://4ort.xyz/entity/centromere-protein-a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P49450)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
5. [Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
6. [HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
7. [Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
8. [Centromere-specific assembly of CENP-a nucleosomes is mediated by HJURP.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
9. [The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
10. [Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
11. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
12. [A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
13. [HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its deposition at centromeres](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450)
16. [The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
17. [Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
18. [Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450)
19. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450)
20. [The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450)
21. [Proteomic characterization of the human sperm nucleus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
22. [Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
23. [Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49450)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49450&geneProductId=UniProtKB:P49450)
25. Ensembl Release 99
26. UMLS 2023