# Center for Research on Inflammation

> facility in Paris, France

**Wikidata**: [Q30261444](https://www.wikidata.org/wiki/Q30261444)  
**Source**: https://4ort.xyz/entity/center-for-research-on-inflammation

## Summary
The Center for Research on Inflammation (CRI) is a specialized research institute based in Paris, France, established in 2014 to advance scientific understanding of inflammatory diseases. Affiliated with major institutions like Assistance Publique–Hôpitaux de Paris (AP-HP) and the French National Institute of Health and Medical Research (Inserm), it conducts interdisciplinary research at the intersection of biology, medicine, and public health. Located in the 18th arrondissement, CRI operates as a hub for fundamental and translational research, supported by partnerships with universities and national research organizations.

## Key Facts
- Founded in 2014 as a dedicated research facility focused on inflammation and immune response.
- Parent organizations include AP-HP, Inserm, Paris Cité University, CNRS, and the Institute of Biological Sciences.
- Located at 16 rue Henri Huchard, 75018 Paris, France (coordinates: 48.898774° N, 2.332291° E).
- Classified as a research institute under schema.org/ResearchOrganization and Wikidata entity Q30141628.
- Identifiers: GRID ID grid.462374.0, ROR ID 02gn50d10, VIAF ID 113145542389996640137, Ringgold ID 89175.
- French national research structure ID: 201420703X; CNRS research group ID: ERL8252.
- Website: http://www.cri1149.fr/en/.
- Part of the French National Center for Scientific Research (CNRS) and Paris Diderot University (now Paris Cité University).

## FAQs
### Q: When was the Center for Research on Inflammation established, and what institutions support it?
A: The CRI was founded in 2014 and is supported by a consortium of French institutions, including AP-HP, Inserm, CNRS, Paris Cité University, and the Institute of Biological Sciences. These partnerships enable collaborative research across medical, academic, and scientific disciplines.

### Q: What is the primary focus of the Center for Research on Inflammation?
A: The CRI specializes in studying inflammation and immune-related disorders, conducting both fundamental research into biological mechanisms and translational studies aimed at developing diagnostic and therapeutic solutions for conditions such as autoimmune diseases, allergies, and chronic inflammatory diseases.

### Q: Where is the Center for Research on Inflammation located, and what facilities does it have?
A: The institute is situated in the 18th arrondissement of Paris at 16 rue Henri Huchard. It operates advanced laboratories and research infrastructure, including specialized units for immunology, molecular biology, and clinical research, supported by its affiliation with major hospitals and universities.

### Q: How does the CRI contribute to global health research?
A: By focusing on inflammation—a key factor in diseases such as arthritis, asthma, and cardiovascular conditions—the CRI addresses critical global health challenges. Its research informs the development of targeted therapies and diagnostic tools, contributing to improved patient outcomes and public health strategies.

## Why It Matters
The Center for Research on Inflammation plays a pivotal role in addressing inflammation-related disorders, which underpin many chronic and acute diseases affecting global populations. As a multidisciplinary institute bridging basic science and clinical practice, the CRI accelerates the translation of laboratory discoveries into medical applications, directly impacting patient care and public health policy. Its collaborative model, integrating hospitals, universities, and national research bodies, exemplifies the synergy required to tackle complex medical challenges. By focusing on inflammation—a universal biological process—the CRI’s work has broad implications for understanding immunity, infection, and tissue repair, contributing to advancements in personalized medicine and therapeutic innovation.

## Notable For
- **Interdisciplinary Research Model**: Combines expertise from immunology, biology, and clinical medicine under one organizational framework.
- **Strategic Partnerships**: Unique collaboration between AP-HP (public hospital network), Inserm (medical research), and CNRS (national science agency).
- **Advanced Infrastructure**: Hosts specialized laboratories and research platforms, including the CNRS-certified ERL8252 group.
- **Global Recognition**: Registered across multiple international identifiers (GRID, ROR, VIAF) and French national systems (IDREF, HAL structure ID 246564).
- **Urban Academic Integration**: Situated in Paris, facilitating direct collaboration with major universities and hospitals.

## Body

### Founding and Structure
The Center for Research on Inflammation was established in 2014 as a consortium-based research institute, merging the resources of Assistance Publique–Hôpitaux de Paris (AP-HP), the French National Institute of Health and Medical Research (Inserm), Paris Diderot University (now Paris Cité University), the National Center for Scientific Research (CNRS), and the Institute of Biological Sciences. This collaborative structure allows the CRI to integrate clinical, academic, and fundamental research, creating a continuum from basic science discovery to bedside application.

### Research Focus
The institute specializes in investigating the molecular and cellular mechanisms of inflammation, with an emphasis on translational research. Key areas include:
- **Immune Response**: Studying how inflammation mediates immune defenses and contributes to diseases such as autoimmune disorders and allergies.
- **Chronic Inflammatory Diseases**: Research into conditions like rheumatoid arthritis, inflammatory bowel disease, and asthma.
- **Infection and Repair**: Exploring inflammation’s dual role in combating pathogens and driving tissue regeneration.

### Geographic and Institutional Context
Located in the 18th arrondissement of Paris at 16 rue Henri Huchard, the CRI benefits from proximity to major academic and medical institutions. Its coordinates (48.898774° N, 2.332291° E) place it within a hub of scientific activity in the French capital. The institute’s street address and geographic positioning are formally documented in international registries, including Geonames (feature code S.ITTR).

### Identifiers and Classifications
The CRI is recognized through a range of international and national identifiers:
- **GRID ID**: grid.462374.0 (Global Research Identifier Database)
- **ROR ID**: 02gn50d10 (Research Organization Registry)
- **VIAF ID**: 113145542389996640137 (Virtual International Authority File)
- **Ringgold ID**: 89175
- **French National Research Structure ID**: 201420703X
- **CNRS Research Group ID**: ERL8252

These identifiers ensure the institute’s research output is traceable across global academic networks and funding platforms.

### Digital Presence and Accessibility
The CRI maintains an official website (http://www.cri1149.fr/en/) and is indexed in the HAL open archive platform (structure ID 246564), promoting transparency and collaboration in scientific research. Its work is further documented in the IdRef system (ID 180760017), a French authority file for research entities.

### Parent Organizations and Collaborations
The institute’s governance involves a consortium of five core institutions:
1. **AP-HP**: Provides clinical expertise and access to patient data for translational studies.
2. **Inserm**: Supports medical research frameworks and funding.
3. **Paris Cité University**: Facilitates academic partnerships and educational programs.
4. **CNRS**: Contributes fundamental science resources and interdisciplinary collaboration.
5. **Institute of Biological Sciences**: Enhances specialized research capabilities in life sciences.

This multi-institutional model enables the CRI to leverage diverse expertise, from molecular biology to public health policy.

### Historical and Regulatory Context
Established in 2014, the CRI aligns with France’s strategic investment in biomedical research, particularly in the wake of the 2008 global financial crisis, which prompted renewed focus on innovation-driven economic growth. The institute complies with national research standards, reflected in its certification by the French National Research Agency (ANR) and integration into the European Research Area (ERA).

### Infrastructure and Resources
The CRI operates advanced research facilities, including:
- **Specialized Laboratories**: Equipped for immunology, molecular biology, and cellular analysis.
- **Clinical Research Units**: Collaborative spaces with AP-HP hospitals for patient-centric studies.
- **Bioinformatics Platforms**: Supporting data-driven research in genomics and proteomics.

These resources are bolstered by the institute’s participation in national infrastructure programs, such as the French National Biobank Network.

### Geopolitical and Cultural Significance
As a Paris-based institute, the CRI benefits from France’s historical prominence in scientific research, dating back to institutions like the Academy of Sciences (founded 1666). Its location in the French capital positions it as a bridge between European and global research communities, fostering partnerships with organizations such as the European Molecular Biology Organization (EMBO) and the World Health Organization (WHO).

### Legacy and Impact
Since its inception, the CRI has contributed to seminal studies on inflammatory pathways, including research on cytokine signaling and immune cell regulation. Its work has informed clinical trials for novel anti-inflammatory therapies and diagnostic biomarkers, addressing unmet medical needs in both developed and low-resource settings. By prioritizing open science and data sharing, the institute amplifies the global impact of its research, aligning with international initiatives like the UNESCO Recommendation on the Ethics of Artificial Intelligence in scientific practice.

## References

1. GRID Release 2017-05-22
2. [Source](https://aurehal.archives-ouvertes.fr/structure/246564)
3. French National Directory of Research Structures
4. Aligned ISNI and Ringgold identifiers for institutions