# Cell division cycle 42

> mammalian protein found in Homo sapiens

**Wikidata**: [Q1198053](https://www.wikidata.org/wiki/Q1198053)  
**Source**: https://4ort.xyz/entity/cell-division-cycle-42


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P60953)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P60953)
5. [Interaction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replication](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
6. [Apolipoprotein A-I activates Cdc42 signaling through the ABCA1 transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
7. [A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P60953)
8. [Role of RacC for the regulation of WASP and phosphatidylinositol 3-kinase during chemotaxis of Dictyostelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
9. [A Dictyostelium homologue of WASP is required for polarized F-actin assembly during chemotaxis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
10. [Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
11. [SPECs, small binding proteins for Cdc42](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
12. [Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
13. [Identification of a novel protein with GDP dissociation inhibitor activity for the ras-like proteins CDC42Hs and rac I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
14. [LRCH1 interferes with DOCK8-Cdc42-induced T cell migration and ameliorates experimental autoimmune encephalomyelitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
15. [A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
16. [The integrin cytoplasmic domain-associated protein ICAP-1 binds and regulates Rho family GTPases during cell spreading](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
17. [Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
18. [Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
19. [EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
20. [A human interactome in three quantitative dimensions organized by stoichiometries and abundances](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
21. [Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
22. [Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
23. [Activation of endogenous Cdc42 visualized in living cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
24. [The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
25. [Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
26. [Histaminylation of glutamine residues is a novel posttranslational modification implicated in G-protein signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
27. [Rac1 Protein Rescues Neurite Retraction Caused by G2019S Leucine-rich Repeat Kinase 2 (LRRK2)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
28. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
29. [A human MAP kinase interactome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
30. [A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
31. [Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
32. [Quantitative mass spectrometry catalogues Salmonella pathogenicity island-2 effectors and identifies their cognate host binding partners](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
33. [Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
34. [Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
35. [ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
36. [Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
37. [Myotonic Dystrophy Kinase-Related Cdc42-Binding Kinase Acts as a Cdc42 Effector in Promoting Cytoskeletal Reorganization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
38. [CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
39. [Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
40. [Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
41. [Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
42. [Rho GTPase Cdc42 Is a Direct Interacting Partner of Adenomatous Polyposis Coli Protein and Can Alter Its Cellular Localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
43. [Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
44. [Invasion of breast cancer cells into collagen matrix requires TGF-α and Cdc42 signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
45. [Structure of Cdc42 in a complex with the GTPase-binding domain of the cell polarity protein, Par6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
46. [Group I and II mammalian PAKs have different modes of activation by Cdc42](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
47. [Identification and characterization of the Cdc42-binding site of IQGAP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
48. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
49. [Blebbishields, the emergency program for cancer stem cells: sphere formation and tumorigenesis after apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)
50. [The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P60953)