# Cell cycle and apoptosis regulator 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21117052](https://www.wikidata.org/wiki/Q21117052)  
**Source**: https://4ort.xyz/entity/cell-cycle-and-apoptosis-regulator-2


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8N163)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/E5RHJ4)
4. Q20641742
5. [DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
6. [Inhibition of SUV39H1 methyltransferase activity by DBC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
8. [Negative regulation of the deacetylase SIRT1 by DBC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
9. [DBC1 is a negative regulator of SIRT1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
10. [Repression of estrogen receptor beta function by putative tumor suppressor DBC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
11. [MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
12. [DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
13. [CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
14. [DBC1 (Deleted in Breast Cancer 1) modulates the stability and function of the nuclear receptor Rev-erbα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
15. [Identification of DBC1 as a transcriptional repressor for BRCA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
16. [HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
17. [Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
18. [Global landscape of HIV-human protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
19. [A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
20. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
21. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
23. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
24. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
25. [Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
27. [Caspase-dependent processing activates the proapoptotic activity of deleted in breast cancer-1 during tumor necrosis factor-alpha-mediated death signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
28. [MCC inhibits beta-catenin transcriptional activity by sequestering DBC1 in the cytoplasm](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
29. [Repression of estrogen receptor beta function by putative tumor suppressor DBC1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
30. [CCAR2 negatively regulates nuclear receptor LXRα by competing with SIRT1 deacetylase](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
31. [Identification of DBC1 as a transcriptional repressor for BRCA1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N163&geneProductId=UniProtKB:Q8N163)
32. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:E5RHJ4)
33. [Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N163)
34. Ensembl Release 99
35. UMLS 2023