# Cdc42 Dmel_CG12530

> protein found in Drosophila melanogaster

**Wikidata**: [Q29814989](https://www.wikidata.org/wiki/Q29814989)  
**Source**: https://4ort.xyz/entity/cdc42-dmel-cg12530


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P40793)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
5. [Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
6. [Roles of the JNK signaling pathway in Drosophila morphogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
7. [Small GTPases and the evolution of the eukaryotic cell](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
9. [The Rac GTPase-activating protein RotundRacGAP interferes with Drac1 and Dcdc42 signalling in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
10. [Unique and Overlapping Functions of Formins Frl and DAAM During Ommatidial Rotation and Neuronal Development in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
11. [Mbt, a Drosophila PAK protein, combines with Cdc42 to regulate photoreceptor cell morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
12. [Genghis Khan (Gek) as a putative effector forDrosophilaCdc42 and regulator of actin polymerization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
13. [Wash functions downstream of Rho and links linear and branched actin nucleation factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
14. [Mbt, a Drosophila PAK protein, combines with Cdc42 to regulate photoreceptor cell morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
15. [A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
16. [The Rac GTPase-activating protein RotundRacGAP interferes with Drac1 and Dcdc42 signalling in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
17. [Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
18. [Roles of the JNK signaling pathway in Drosophila morphogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
19. [Small GTPases and the evolution of the eukaryotic cell](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
21. [A Drosophila homolog of the Rac- and Cdc42-activated serine/threonine kinase PAK is a potential focal adhesion and focal complex protein that colocalizes with dynamic actin structures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
22. [Endogenous activation patterns of Cdc42 GTPase within Drosophila embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
23. [Endogenous activation patterns of Cdc42 GTPase within Drosophila embryos](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
24. [A Cdc42-regulated actin cytoskeleton mediates Drosophila oocyte polarization.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
25. [WASp is required for the correct temporal morphogenesis of rhabdomere microvilli](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
26. [Growth cone pathfinding and filopodial dynamics are mediated separately by Cdc42 activation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
27. [Positive feedback and mutual antagonism combine to polarize Crumbs in the Drosophila follicle cell epithelium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
28. [A Cdc42-regulated actin cytoskeleton mediates Drosophila oocyte polarization.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
29. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
30. [Rab35 mediates transport of Cdc42 and Rac1 to the plasma membrane during phagocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
31. [A genome-wide resource for the analysis of protein localisation in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
32. [The RhoGEF Zizimin-related acts in the Drosophila cellular immune response via the Rho GTPases Rac2 and Cdc42.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
33. [Signaling pathways directing the movement and fusion of epithelial sheets: lessons from dorsal closure in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
34. [The RhoGEF Zizimin-related acts in the Drosophila cellular immune response via the Rho GTPases Rac2 and Cdc42.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
35. [The RhoGAP crossveinless-c interacts with Dystrophin and is required for synaptic homeostasis at the Drosophila neuromuscular junction.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
36. [The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
37. [How one becomes many: blastoderm cellularization in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
38. [The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
39. [Genes regulating dendritic outgrowth, branching, and routing in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
40. [Regulation of rho family GTPases is required to prevent axons from crossing the midline](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
41. [Frazzled regulation of myosin II activity in the Drosophila embryonic CNS.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
42. [Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
43. [Nervous wreck and Cdc42 cooperate to regulate endocytic actin assembly during synaptic growth.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
44. [dCIP4 (Drosophila Cdc42-interacting protein 4) restrains synaptic growth by inhibiting the secretion of the retrograde Glass bottom boat signal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
45. [Polarity proteins and Rho GTPases cooperate to spatially organise epithelial actin-based protrusions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
46. [Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
47. [Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
48. [Translational regulation and RNA localization in Drosophila oocytes and embryos.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P40793&geneProductId=UniProtKB:P40793)
49. [Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)
50. [Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P40793)