# CD8a molecule

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21100581](https://www.wikidata.org/wiki/Q21100581)  
**Source**: https://4ort.xyz/entity/cd8a-molecule


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P01732)
3. Q20641742
4. [Calyculin A inhibits expression of CD8alpha but not CD4 in human peripheral blood T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
5. [Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
6. [The CD4 and CD8 antigens are coupled to a protein-tyrosine kinase (p56lck) that phosphorylates the CD3 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
7. [Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
8. [Molecular biology and function of CD4 and CD8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
10. [Polymorphism in the alpha 3 domain of HLA-A molecules affects binding to CD8.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
11. [Alternatively spliced mRNA encodes a secreted form of human CD8 alpha. Characterization of the human CD8 alpha gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
12. [CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
13. [FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01732&geneProductId=UniProtKB:P01732)
14. [FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
16. [Zinc is essential for binding of p56(lck) to CD4 and CD8alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01732)
17. Ensembl Release 99