# CD81 molecule

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21131199](https://www.wikidata.org/wiki/Q21131199)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/CD81)  
**Source**: https://4ort.xyz/entity/cd81-molecule


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P60033)
3. Q20641742
4. [Claudin association with CD81 defines hepatitis C virus entry.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
5. [Dimeric association and segmental variability in the structure of human CD4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
6. [EWI-2 is a major CD9 and CD81 partner and member of a novel Ig protein subfamily](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
7. [SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
8. [TAPA-1, the target of an antiproliferative antibody, is associated on the cell surface with the Leu-13 antigen](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
9. [Tetraspanin CD81 is linked to ERK/MAPKinase signaling by Shc in liver tumor cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
10. [Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
11. [Identification of a lactoferrin-derived peptide possessing binding activity to hepatitis C virus E2 envelope protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
12. [Binding of hepatitis C virus to CD81](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
13. [Analysis of the subcellular localization of hepatitis C virus E2 glycoprotein in live cells using EGFP fusion proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
14. [CD81 is dispensable for hepatitis C virus cell-to-cell transmission in hepatoma cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
15. [Comparative Proteomics Reveals Important Viral-Host Interactions in HCV-Infected Human Liver Cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
16. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
17. [CD81 Promotes Both the Degradation of Transferrin Receptor 2 (TfR2) and the Tfr2-mediated Maintenance of Hepcidin Expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
19. [The CD9, CD81, and CD151 EC2 domains bind to the classical RGD-binding site of integrin αvβ3.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
20. [Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
21. [NAG-2, a Novel Transmembrane-4 Superfamily (TM4SF) Protein That Complexes with Integrins and Other TM4SF Proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
22. [Defining the membrane proteome of NK cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
23. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
24. [Proteomic profiling of human plasma exosomes identifies PPARgamma as an exosome-associated protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
25. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
26. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
27. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
28. [Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
29. [Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
30. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
31. [Exosomal-like vesicles are present in human blood plasma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
32. [CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
33. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
34. [TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P60033&geneProductId=UniProtKB:P60033)
35. Ensembl Release 99
36. UMLS 2023
37. Transporter Classification database
38. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)