# CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

> mammalian protein found in Mus musculus

**Wikidata**: [Q21428393](https://www.wikidata.org/wiki/Q21428393)  
**Source**: https://4ort.xyz/entity/cd74-antigen-invariant-polypeptide-of-major-histocompatibility-complex-class-ii-antigen-associated-


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P04441)
3. Q20641742
4. [Reconstitution of an operational MHC class II compartment in nonantigen-presenting cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
6. [Nitric-oxide synthase 2 interacts with CD74 and inhibits its cleavage by caspase during dendritic cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
7. [CD1d Endosomal Trafficking Is Independently Regulated by an Intrinsic CD1d-Encoded Tyrosine Motif and by the Invariant Chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
8. [Macrophage migration inhibitory factor induces B cell survival by activation of a CD74-CD44 receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
9. [MIF signal transduction initiated by binding to CD74](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
10. [Dynamics of major histocompatibility complex class II compartments during B cell receptor-mediated cell activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
11. [Endoplasmic reticulum-associated degradation-induced dissociation of class II invariant chain complexes containing a glycosylation-deficient form of p41](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
12. [Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
13. [The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
14. [Mice lacking the MHC class II-associated invariant chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
15. [T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
16. [A novel mutation in CD83 results in the development of a unique population of CD4+ T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
17. [Invariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
18. [Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
19. [Invariant chain is the core protein of the Ia-associated chondroitin sulfate proteoglycan](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
20. [CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
21. [Macrophage CD74 contributes to MIF-induced pulmonary inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
22. [Preferential Th1 immune response in invariant chain-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P04441)
23. ensembl Release 106