# CD4 antigen

> mammalian protein found in Mus musculus

**Wikidata**: [Q14865413](https://www.wikidata.org/wiki/Q14865413)  
**Source**: https://4ort.xyz/entity/cd4-antigen


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P06332)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
6. [Interaction of p56lck with CD4 in the yeast two-hybrid system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
7. [Lck availability during thymic selection determines the recognition specificity of the T cell repertoire](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
8. [Interactions between the amino‐terminal domain of p56lck and cytoplasmic domains of CD4 and CD8α in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
10. [The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
11. [The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
12. [Microfilament-associated Protein 7 Increases the Membrane Expression of Transient Receptor Potential Vanilloid 4 (TRPV4)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
13. [The specificity and orientation of a TCR to its peptide-MHC class II ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P06332)
14. [CD4 raft association and signaling regulate molecular clustering at the immunological synapse site](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
15. [FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
16. [Serine protease inhibitors serpina1 and serpina3 are down-regulated in bone marrow during hematopoietic progenitor mobilization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
17. [GATA-3 is required for early T lineage progenitor development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
18. [Evidence that CD4+, but not CD8+ T cells are responsible for murine interleukin‐2‐deficient colitis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
19. [Essential role for ZAP-70 in both positive and negative selection of thymocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
20. [CDK6 kinase activity is required for thymocyte development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
21. [Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
22. [The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
23. [Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
24. [Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
25. [Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
26. [A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
27. [Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
28. [BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
29. [Differential T cell costimulatory requirements in CD28-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
30. [Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
31. [Accessory protein-like is essential for IL-18-mediated signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
32. [T lymphocytes amplify the anabolic activity of parathyroid hormone through Wnt10b signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
33. [A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
34. [Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
35. [Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
36. [Glycosyltransferase function in core 2-type protein O glycosylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
37. [Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
38. [The sequential activity of Gata3 and Thpok is required for the differentiation of CD1d-restricted CD4+ NKT cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
39. [CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
40. [Increased Foxp3(+) CD4(+) regulatory T cells with intact suppressive activity but altered cellular localization in murine lupus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
41. [Successful elimination of memory-type CD8+ T cell subsets by the administration of anti-Gr-1 monoclonal antibody in vivo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
42. [The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
43. [A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
44. [Cutting edge: molecular analysis of the negative regulatory function of lymphocyte activation gene-3](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
45. [GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
46. [GATA-3 regulates the development and function of invariant NKT cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
47. [SCART scavenger receptors identify a novel subset of adult gammadelta T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
48. [MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
49. [A novel mutation in CD83 results in the development of a unique population of CD4+ T cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)
50. [A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P06332&geneProductId=UniProtKB:P06332)