# CD3e molecule

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7667899](https://www.wikidata.org/wiki/Q7667899)  
**Source**: https://4ort.xyz/entity/cd3e-molecule


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P07766)
3. Q20641742
4. [Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07766&geneProductId=UniProtKB:P07766)
6. [Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits proximal TCR signaling by targeting ZAP-70](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
7. [Analysis of the interaction of ZAP-70 and syk protein-tyrosine kinases with the T-cell antigen receptor by plasmon resonance](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
8. [Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
9. [Interaction between the N-terminal SH3 domain of Nck-alpha and CD3-epsilon-derived peptides: non-canonical and canonical recognition motifs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
10. [Structural basis of PxxDY motif recognition in SH3 binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
11. [Reciprocal regulation of SH3 and SH2 domain binding via tyrosine phosphorylation of a common site in CD3epsilon](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
12. [Phosphorylation of the N-terminal and C-terminal CD3-epsilon-ITAM tyrosines is differentially regulated in T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
13. [Assembly of the TCR/CD3 complex: CD3ε/δ and CD3ε/γ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
14. [T lymphocyte development in the absence of CD3 epsilon or CD3 gamma delta epsilon zeta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
15. [Fourteen years' follow-up of an autoimmune patient lacking the CD3 gamma subunit of the T-lymphocyte receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
16. [Assembly of the TCR/CD3 complex: CD3ε/δ and CD3ε/γ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07766&geneProductId=UniProtKB:P07766)
17. [Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
20. [The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
21. [Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
22. [The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07766&geneProductId=UniProtKB:P07766)
23. [FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07766&geneProductId=UniProtKB:P07766)
24. [FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
25. [Overexpression of Bcl-2 inhibited T lymphocyte apoptosis mediated by CD3 epsilon molecule](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
26. [Interaction between G proteins and tyrosine kinases upon T cell receptor.CD3-mediated signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
27. [Independent mutations of the human CD3-epsilon gene resulting in a T cell receptor/CD3 complex immunodeficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
28. [Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
29. [Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07766&geneProductId=UniProtKB:P07766)
30. [SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07766)
31. Ensembl Release 99
32. Transporter Classification database