# CD3 antigen, epsilon polypeptide

> mammalian protein found in Mus musculus

**Wikidata**: [Q21981008](https://www.wikidata.org/wiki/Q21981008)  
**Source**: https://4ort.xyz/entity/cd3-antigen-epsilon-polypeptide


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P22646)
3. Q20641742
4. [Essential role for ZAP-70 in both positive and negative selection of thymocytes](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
5. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
6. [Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
9. [The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
10. [A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
11. [Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
12. [Age-related defects in CD4+ T cell activation reversed by glycoprotein endopeptidase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
13. [A single class II myosin modulates T cell motility and stopping, but not synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
14. [FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
15. [Interchangeability of Themis1 and Themis2 in Thymocyte Development Reveals Two Related Proteins with Conserved Molecular Function](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
16. [Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
17. [A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
18. [MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
19. [Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
20. [Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
21. [Heat-stable antigen/CD24 on mouse T lymphocytes: evidence for a costimulatory function](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
22. [BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
23. [CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
24. [MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
25. [Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
26. [CD3 and immunoglobulin G Fc receptor regulate cerebellar functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
27. [FcRL6, a new ITIM-bearing receptor on cytolytic cells, is broadly expressed by lymphocytes following HIV-1 infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
28. [Deletion of the mouse T-cell receptor beta gene enhancer blocks alphabeta T-cell development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
29. [Stat5 activation is uniquely associated with cytokine signaling in peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
30. [MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
31. [Essential role for ZAP-70 in both positive and negative selection of thymocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
32. [Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
33. [BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
34. [A complementary role for the tetraspanins CD37 and Tssc6 in cellular immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
35. [Heat-stable antigen/CD24 on mouse T lymphocytes: evidence for a costimulatory function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
36. [CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
37. [Interchangeability of Themis1 and Themis2 in Thymocyte Development Reveals Two Related Proteins with Conserved Molecular Function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
38. [MicroRNAs enriched in hematopoietic stem cells differentially regulate long-term hematopoietic output](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
39. [Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
40. [Signaling capacity of the T cell antigen receptor is negatively regulated by the PTP1C tyrosine phosphatase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
41. [A spontaneously arising mutation in the DLAARN motif of murine ZAP-70 abrogates kinase activity and arrests thymocyte development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
42. [Negative regulation of lymphocyte activation by the adaptor protein LAX](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
43. [Enhancement of CD3-mediated thymocyte apoptosis by the cross-linkage of heat-stable antigen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
44. [Involvement of receptor-interacting protein 2 in innate and adaptive immune responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
45. [Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
46. [Enhancement of CD3-mediated thymocyte apoptosis by the cross-linkage of heat-stable antigen](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P22646)
47. [Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
48. [Adenosine inhibits activation-induced T cell expression of CD2 and CD28 co-stimulatory molecules: role of interleukin-2 and cyclic AMP signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
49. [SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P22646)
50. ensembl Release 106