# CD247 molecule

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21102029](https://www.wikidata.org/wiki/Q21102029)  
**Source**: https://4ort.xyz/entity/cd247-molecule-q21102029


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P20963)
3. Q20641742
4. [BY55/CD160 acts as a co-receptor in TCR signal transduction of a human circulating cytotoxic effector T lymphocyte subset lacking CD28 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
5. [A novel Src homology 2 domain-containing molecule, Src-like adapter protein-2 (SLAP-2), which negatively regulates T cell receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
6. [A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
7. [ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
8. [CD81 controls sustained T cell activation signaling and defines the maturation stages of cognate immunological synapses.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
9. [End-binding protein 1 controls signal propagation from the T cell receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
10. [Mechanism of activation for Zap-70 catalytic activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
11. [β-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
12. [Interaction between the SH2 domains of ZAP-70 and the tyrosine-based activation motif 1 sequence of the zeta subunit of the T-cell receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
13. [The Adaptor Protein SAP Directly Associates with CD3ζ Chain and Regulates T Cell Receptor Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
14. [T cell receptor engagement triggers its CD3epsilon and CD3zeta subunits to adopt a compact, locked conformation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
15. [Alternative modes of binding of proteins with tandem SH2 domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
16. [Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
17. [Human and mouse killer-cell inhibitory receptors recruit PTP1C and PTP1D protein tyrosine phosphatases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
18. [Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
19. [Peptide microarrays for the detection of molecular interactions in cellular signal transduction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
20. [The Transmembrane Adaptor Protein SIT Inhibits TCR-Mediated Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
21. [Identification of substrates of human protein-tyrosine phosphatase PTPN22](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
23. [The structure of the zetazeta transmembrane dimer reveals features essential for its assembly with the T cell receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
24. [Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
25. [Phosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
26. [Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
27. [The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
28. [A new subunit of the human T-cell antigen receptor complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
29. [Five novel antigens illustrate shared phenotype between mouse thymic stromal cells, thymocytes, and peripheral lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
30. [Differential expression of ZAP-70 and Syk protein tyrosine kinases, and the role of this family of protein tyrosine kinases in TCR signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
31. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20963)
32. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P20963&geneProductId=UniProtKB:P20963)
33. Ensembl Release 99
34. Transporter Classification database