DNA-binding transcription factor activity
regulation of transcription, DNA-templated
regulation of gene expression, epigenetic
regulation of centromeric sister chromatid cohesion
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes
A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers
Critical DNA binding interactions of the insulator protein CTCF: a small number of zinc fingers mediate strong binding, and a single finger-DNA interaction controls binding at imprinted loci
Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2
CTCF Recruits Centromeric Protein CENP-E to the Pericentromeric/Centromeric Regions of Chromosomes through Unusual CTCF-Binding Sites
JARID1B is a luminal lineage-driving oncogene in breast cancer
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting
Vigilin interacts with CCCTC‐binding factor (CTCF) and is involved in CTCF‐dependent regulation of the imprinted genes Igf2 and H19
A proteome-scale map of the human interactome network
A census of human transcription factors: function, expression and evolution
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin
Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly(ADP-ribosyl)ation-dependent mechanism
CTCF physically links cohesin to chromatin
CTCF genetic alterations in endometrial carcinoma are pro-tumorigenic.
The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2
Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster
DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation
The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions