# CCAAT enhancer binding protein alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21116819](https://www.wikidata.org/wiki/Q21116819)  
**Source**: https://4ort.xyz/entity/ccaat-enhancer-binding-protein-alpha-q21116819


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P49715)
3. Q20641742
4. [The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
6. [STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
7. [Transcription factor C/EBPalpha: novel sites of expression and cloning of the human gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
8. [Chromosomal localization in man and rat of the genes encoding the liver-enriched transcription factors C/EBP, DBP, and HNF1/LFB-1 (CEBP, DBP, and transcription factor 1, TCF1, respectively) and of the hepatocyte growth factor/scatter factor gene (HG](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
9. [Signal transducers and activators of transcription 3 augments the transcriptional activity of CCAAT/enhancer-binding protein alpha in granulocyte colony-stimulating factor signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
10. [Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
11. [Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
13. [Hepatitis C Virus-Induced Changes in MicroRNA 107 (miRNA-107) and miRNA-449a Modulate CCL2 by Targeting the Interleukin-6 Receptor Complex in Hepatitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
14. [Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
15. [Homeodomain transcription factor CDX1 is required for the transcriptional induction of PPARgamma in intestinal cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
16. [The Papillomavirus E2 protein binds to and synergizes with C/EBP factors involved in keratinocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
17. [Interleukin (IL)-32β-mediated CCAAT/enhancer-binding protein α (C/EBPα) phosphorylation by protein kinase Cδ (PKCδ) abrogates the inhibitory effect of C/EBPα on IL-10 production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
18. [In prostate cancer cells the interaction of C/EBPalpha with Ku70, Ku80, and poly(ADP-ribose) polymerase-1 increases sensitivity to DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
19. [Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
20. [Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
21. [Molecular cloning, sequence, and expression patterns of the human gene encoding CCAAT/enhancer binding protein alpha (C/EBP alpha)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
22. [Nucleolar retention of a translational C/EBPalpha isoform stimulates rDNA transcription and cell size](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
23. [Roles of CHOP/GADD153 in endoplasmic reticulum stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
24. [Signal transducers and activators of transcription 3 augments the transcriptional activity of CCAAT/enhancer-binding protein alpha in granulocyte colony-stimulating factor signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
25. [STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
26. [NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
27. [Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
28. [The CCAAT enhancer-binding protein alpha (C/EBPalpha) requires a SWI/SNF complex for proliferation arrest](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
29. [EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P49715&geneProductId=UniProtKB:P49715)
30. [NF-kappa B and C/EBP transcription factor families synergistically function in mouse serum amyloid A gene expression induced by inflammatory cytokines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
31. [Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P49715)
32. Ensembl Release 99
33. UMLS 2023