# Caveolin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21115385](https://www.wikidata.org/wiki/Q21115385)  
**Source**: https://4ort.xyz/entity/caveolin-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q03135)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
5. [The regulation of the cardiac potassium channel (HERG) by caveolin-1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03135&geneProductId=UniProtKB:Q03135)
6. [Identification and characterization of a novel human plant pathogenesis-related protein that localizes to lipid-enriched microdomains in the Golgi complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03135&geneProductId=UniProtKB:Q03135)
7. [Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
8. [Caveolae and caveolin-1 in human term villous trophoblast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
9. [The sonic hedgehog receptor patched associates with caveolin-1 in cholesterol-rich microdomains of the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
10. [The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
11. [Syntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
12. [Cavin3 interacts with cavin1 and caveolin1 to increase surface dynamics of caveolae.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
13. [Interaction of deleted in liver cancer 1 with tensin2 in caveolae and implications in tumor suppression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
14. [MLC1 trafficking and membrane expression in astrocytes: role of caveolin-1 and phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
15. [Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
16. [Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
17. [Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
18. [Caveolin-1 mediates Fas–BID signaling in hyperoxia-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
19. [Some protein tyrosine phosphatases target in part to lipid rafts and interact with caveolin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
20. [Molecular composition and ultrastructure of the caveolar coat complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
21. [Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
22. [Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
23. [SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
24. [The regulation of the cardiac potassium channel (HERG) by caveolin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
25. [The Niemann-Pick C1 and caveolin-1 proteins interact to modulate efflux of low density lipoprotein-derived cholesterol from late endocytic compartments](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
26. [Caveolin-1 Mediates Salmonella Invasion via the Regulation of SopE-dependent Rac1 Activation and Actin Reorganization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
27. [TLR4-mediated expulsion of bacteria from infected bladder epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
28. [Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
29. [Dynamic profiling of the post-translational modifications and interaction partners of epidermal growth factor receptor signaling after stimulation by epidermal growth factor using Extended Range Proteomic Analysis (ERPA)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
30. [Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
31. [Identification of a novel inhibitor of differentiation-1 (ID-1) binding partner, caveolin-1, and its role in epithelial-mesenchymal transition and resistance to apoptosis in prostate cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
32. [Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
33. [Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
34. [Identification of phosphocaveolin-1 as a novel protein tyrosine phosphatase 1B substrate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
35. [Tyrosine-phosphorylated caveolin-1 blocks bacterial uptake by inducing Vav2-RhoA-mediated cytoskeletal rearrangements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
36. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
37. [Flotillins/cavatellins are differentially expressed in cells and tissues and form a hetero-oligomeric complex with caveolins in vivo. Characterization and epitope-mapping of a novel flotillin-1 monoclonal antibody probe](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
38. [Membrane glucocorticoid receptor activation induces proteomic changes aligning with classical glucocorticoid effects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
39. [Tyrosine phosphorylation of caveolin-2 at residue 27: differences in the spatial and temporal behavior of phospho-Cav-2 (pY19 and pY27).](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
40. [Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
41. [Sterol carrier protein-2 directly interacts with caveolin-1 in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
42. [New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
43. [Factor X/Xa Elicits Protective Signaling Responses in Endothelial Cells Directly via PAR-2 and Indirectly via Endothelial Protein C Receptor-dependent Recruitment of PAR-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
44. [BENE, a novel raft-associated protein of the MAL proteolipid family, interacts with caveolin-1 in human endothelial-like ECV304 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
45. [Maxi-K channels localize to caveolae in human myometrium: a role for an actin-channel-caveolin complex in the regulation of myometrial smooth muscle K+ current](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
46. [Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
47. [Tissue factor induction by protease-activated receptor 1 requires intact caveolin-enriched membrane microdomains in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03135)
48. [Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03135&geneProductId=UniProtKB:Q03135)
49. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03135&geneProductId=UniProtKB:Q03135)
50. [Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03135&geneProductId=UniProtKB:Q03135)