Cathepsin K
type: Thing
description: mammalian protein found in Mus musculus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P55097
additional property: PropertyValue
  property ID: P637
  value: NP_031828
additional property: PropertyValue
  property ID: P680
  value: fibronectin binding
additional property: PropertyValue
  property ID: P680
  value: peptidase activity
additional property: PropertyValue
  property ID: P680
  value: cysteine-type endopeptidase activity
additional property: PropertyValue
  property ID: P681
  value: extracellular space
additional property: PropertyValue
  property ID: P681
  value: nucleoplasm
additional property: PropertyValue
  property ID: P681
  value: intracellular membrane-bounded organelle
additional property: PropertyValue
  property ID: P682
  value: collagen catabolic process
additional property: PropertyValue
  property ID: P682
  value: intramembranous ossification
additional property: PropertyValue
  property ID: P682
  value: proteolysis involved in cellular protein catabolic process
additional property: PropertyValue
  property ID: P702
  value: Ctsk
additional property: PropertyValue
  property ID: P703
  value: house mouse
additional property: PropertyValue
  property ID: P705
  value: ENSMUSP00000015664
confidence:
  popularity graph score:
    score: 0.001
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 7
      unique citations norm: 0.003
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 7
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P55097
    source count: 1
    confidence: 0.2
  P637:
    value: NP_031828
    source count: 1
    confidence: 0.2
  P680:
    value: Q14905250
    source count: 2
    confidence: 0.4
    value label: fibronectin binding
  P680:
    value: Q14645703
    source count: 1
    confidence: 0.2
    value label: peptidase activity
  P680:
    value: Q14864228
    source count: 3
    confidence: 0.6
    value label: cysteine-type endopeptidase activity
  P680:
    value: Q14864241
    source count: 2
    confidence: 0.4
    value label: cysteine-type peptidase activity
  P680:
    value: Q14353168
    source count: 1
    confidence: 0.2
    value label: hydrolase activity
  P681:
    value: Q1385443
    source count: 3
    confidence: 0.6
    value label: extracellular space
  P681:
    value: Q14817956
    source count: 2
    confidence: 0.4
    value label: nucleoplasm
  P681:
    value: Q14349519
    source count: 2
    confidence: 0.4
    value label: intracellular membrane-bounded organelle
  P681:
    value: Q79899
    source count: 2
    confidence: 0.4
    value label: cytoplasm
  P681:
    value: Q83330
    source count: 4
    confidence: 0.8
    value label: lysosome
  P682:
    value: Q14877619
    source count: 2
    confidence: 0.4
    value label: collagen catabolic process
  P682:
    value: Q10746904
    source count: 1
    confidence: 0.2
    value label: intramembranous ossification
  P682:
    value: Q14911964
    source count: 3
    confidence: 0.6
    value label: proteolysis involved in cellular protein catabolic process
  P682:
    value: Q33123
    source count: 2
    confidence: 0.4
    value label: proteolysis
  P682:
    value: Q4941581
    source count: 2
    confidence: 0.4
    value label: bone resorption
  P702:
    value: Q14902046
    source count: 1
    confidence: 0.2
    value label: Ctsk
  P703:
    value: Q83310
    source count: 1
    confidence: 0.2
    value label: house mouse
  P705:
    value: ENSMUSP00000015664
    source count: 1
    confidence: 0.2
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2019-02-14
citations:
  source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
  stated in qid: Q34211397
  retrieved: 2019-02-14
citations:
  source: GOA
  stated in qid: Q28018111
  retrieved: 2018-04-24
citations:
  source: Glycosaminoglycan-mediated loss of cathepsin K collagenolytic activity in MPS I contributes to osteoclast and growth plate abnormalities
  stated in qid: Q37413691
  retrieved: 2019-02-14
citations:
  source: UniProt
  stated in qid: Q905695
  retrieved: 2022-05-25
citations:
  source: Q20641742
  stated in qid: Q20641742
  retrieved: 2022-03-20
citations:
  source: ensembl Release 106
  stated in qid: Q111699881

wikidata id: Q14902054
domain: protein
level: standard
html url: https://4ort.xyz/entity/cathepsin-k
markdown url: https://4ort.xyz/entity/cathepsin-k.md
facts url summary: https://4ort.xyz/entity/cathepsin-k/facts.json
facts url standard: https://4ort.xyz/entity/cathepsin-k/facts.json
facts url full: https://4ort.xyz/entity/cathepsin-k/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T06:34:50.756850Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:10:53.568599+00:00Z