# Cathepsin D

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21157699](https://www.wikidata.org/wiki/Q21157699)  
**Source**: https://4ort.xyz/entity/cathepsin-d-q21157699


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P07339)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
5. [Aluminum inhibits proteolytic degradation of amyloid beta peptide by cathepsin D: a potential link between aluminum accumulation and neuritic plaque deposition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
7. [Cloning and sequence analysis of cDNA for human cathepsin D](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
9. [Folding, activity and targeting of mutated human cathepsin D that cannot be processed into the double-chain form](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
10. [Cathepsin D-mediated proteolysis of apolipoprotein E: possible role in Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
11. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
12. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
13. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
14. [Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
15. [Proteomics characterization of extracellular space components in the human aorta](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
16. [Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
17. [Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
18. [Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
19. [Human colostrum: identification of minor proteins in the aqueous phase by proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
20. [The human plasma proteome: a nonredundant list developed by combination of four separate sources](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
21. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07339&geneProductId=UniProtKB:P07339)
22. [The human plasma proteome: a nonredundant list developed by combination of four separate sources](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
23. [Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
24. [Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
25. [Human colostrum: identification of minor proteins in the aqueous phase by proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
26. [Proteomics characterization of extracellular space components in the human aorta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
27. [Lysosomal hydrolases of different classes are abnormally distributed in brains of patients with Alzheimer disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
28. [Nogo-B receptor stabilizes Niemann-Pick type C2 protein and regulates intracellular cholesterol trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
29. [Lysosomal proteinase antigens are prominently localized within senile plaques of Alzheimer's disease: evidence for a neuronal origin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
30. [Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
31. [Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
32. [Proteomic characterization of human multiple myeloma bone marrow extracellular matrix.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
33. [Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
34. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
35. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
36. [Microinjection of cathepsin d induces caspase-dependent apoptosis in fibroblasts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07339)
37. Ensembl Release 99
38. UMLS 2023