# Caspase 3

> mammalian protein found in Mus musculus

**Wikidata**: [Q14914375](https://www.wikidata.org/wiki/Q14914375)  
**Source**: https://4ort.xyz/entity/caspase-3-q14914375


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
4. [Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
6. [Comparative analysis of apoptosis and inflammation genes of mice and humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
7. [Caspase 3 deficiency rescues peripheral nervous system defect in retinoblastoma nullizygous mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
8. [Caspases 3 and 7: key mediators of mitochondrial events of apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
9. [Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
10. [Ischemic preconditioning by caspase cleavage of poly(ADP-ribose) polymerase-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
11. [Molecular Components of a Cell Death Pathway Activated by Endoplasmic Reticulum Stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
12. [p73 is required for survival and maintenance of CNS neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
13. [Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
14. [Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
15. [Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
16. [Nek5, a novel substrate for caspase‐3, promotes skeletal muscle differentiation by up‐regulating caspase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
17. [BAD is a pro-survival factor prior to activation of its pro-apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
18. [Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
19. [Huntingtin inhibits caspase-3 activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
20. [BDNF and NT4 play interchangeable roles in gustatory development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
21. [Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
22. [The role of Asp-462 in regulating Akt activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
23. [Targeted disruption of the murine large nuclear KIAA1440/Ints1 protein causes growth arrest in early blastocyst stage embryos and eventual apoptotic cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
24. [BDNF and NT4 play interchangeable roles in gustatory development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
25. [Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
27. [Nek5, a novel substrate for caspase‐3, promotes skeletal muscle differentiation by up‐regulating caspase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
28. [BAD is a pro-survival factor prior to activation of its pro-apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
29. [Maintenance of muscle stem-cell quiescence by microRNA-489](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
30. [Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
31. [Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
32. [Role of prodomain in importin-mediated nuclear localization and activation of caspase-2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
33. [Cyclooxygenase-2-dependent phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in renal medullary cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
34. [Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
35. [Role of prodomain in importin-mediated nuclear localization and activation of caspase-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
36. [Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFβ-mediated axonogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
37. [Cyclooxygenase-2-dependent phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in renal medullary cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
38. [High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
39. [Deafness due to degeneration of cochlear neurons in caspase-3-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
40. [High commitment of embryonic keratinocytes to terminal differentiation through a Notch1-caspase 3 regulatory mechanism](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
41. [DNA damage-induced neural precursor cell apoptosis requires p53 and caspase 9 but neither Bax nor caspase 3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
42. [Apoptosis and related proteins in placenta of intrauterine fetal death in prostaglandin f receptor-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
43. [An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
44. [Enhanced Oligodendrocyte Survival after Spinal Cord Injury in Bax-Deficient Mice and Mice with Delayed Wallerian Degeneration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
45. [Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
46. [Epistatic and independent functions of caspase-3 and Bcl-X(L) in developmental programmed cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
47. [Involvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
48. [Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P70677)
49. [Caspases 3 and 7: key mediators of mitochondrial events of apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)
50. [Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P70677&geneProductId=UniProtKB:P70677)