# Caspase 10

> mammalian protein found in Homo sapiens

**Wikidata**: [Q22679036](https://www.wikidata.org/wiki/Q22679036)  
**Source**: https://4ort.xyz/entity/caspase-10-q22679036


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL197672)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q92851)
4. Q20641742
5. [Caspase-10 is an initiator caspase in death receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
7. [Caspase-8 and caspase-10 activate NF-kappaB through RIP, NIK and IKKalpha kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
8. [Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
9. [Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
10. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
11. [Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
12. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
13. [Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
14. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
15. [RIOK3 interacts with caspase-10 and negatively regulates the NF-kappaB signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
16. [Suppression of caspase-8- and -10-associated RING proteins results in sensitization to death ligands and inhibition of tumor cell growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92851&geneProductId=UniProtKB:Q92851)
18. [In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
19. [Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
20. [Protective role of Cop in Rip2/caspase-1/caspase-4-mediated HeLa cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
21. [Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92851&geneProductId=UniProtKB:Q92851)
22. [Caspase-10 is an initiator caspase in death receptor signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92851&geneProductId=UniProtKB:Q92851)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
24. [Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
25. [cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92851)
26. [Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92851&geneProductId=UniProtKB:Q92851)
27. Ensembl Release 99