# CASP2 and RIPK1 domain containing adaptor with death domain

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21105410](https://www.wikidata.org/wiki/Q21105410)  
**Source**: https://4ort.xyz/entity/casp2-and-ripk1-domain-containing-adaptor-with-death-domain-q21105410


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P78560)
3. Q20641742
4. [CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
5. [RAIDD is a new 'death' adaptor molecule](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
6. [Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
7. [The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
8. [Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
9. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
10. [Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
11. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
12. [Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
13. [Pooled-matrix protein interaction screens using Barcode Fusion Genetics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
14. [CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP](http://www.ebi.ac.uk/QuickGO/annotations?protein=P78560&geneProductId=UniProtKB:P78560)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P78560&geneProductId=UniProtKB:P78560)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
18. [Expression of the Bcl-2 protein BAD promotes prostate cancer growth](http://www.ebi.ac.uk/QuickGO/annotations?protein=P78560&geneProductId=UniProtKB:P78560)
19. [Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop](http://www.ebi.ac.uk/QuickGO/annotations?protein=P78560&geneProductId=UniProtKB:P78560)
20. [CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
21. [Caspase-2-Mediated Cleavage of Mdm2 Creates a p53-Induced Positive Feedback Loop](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
22. [Expression of the Bcl-2 protein BAD promotes prostate cancer growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P78560)
23. Ensembl Release 99
24. UMLS 2023