# CASC3 exon junction complex subunit

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21110543](https://www.wikidata.org/wiki/Q21110543)  
**Source**: https://4ort.xyz/entity/casc3-exon-junction-complex-subunit


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15234)
3. Q20641742
4. [NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
5. [The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
6. [The cryo-EM structure of the UPF-EJC complex shows UPF1 poised toward the RNA 3' end.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
7. [Disassembly of exon junction complexes by PYM](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
8. [Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
9. [Insights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
10. [The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
11. [An eIF4AIII-containing complex required for mRNA localization and nonsense-mediated mRNA decay](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
12. [The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
13. [The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
14. [Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
15. [Metastatic Lymph Node 51, a novel nucleo-cytoplasmic protein overexpressed in breast cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
16. [RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15234&geneProductId=UniProtKB:O15234)
18. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15234&geneProductId=UniProtKB:O15234)
19. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15234&geneProductId=UniProtKB:O15234)
20. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
21. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
22. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
23. [Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15234&geneProductId=UniProtKB:O15234)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
25. [Structure of a human catalytic step I spliceosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15234)
26. Ensembl Release 99
27. Transporter Classification database