# Cannabinoid receptor 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561621](https://www.wikidata.org/wiki/Q28561621)  
**Source**: https://4ort.xyz/entity/cannabinoid-receptor-1-q28561621


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P20272)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
5. [Structure of a cannabinoid receptor and functional expression of the cloned cDNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
6. [Cannabinoid CB1 receptor antagonists cause status epilepticus-like activity in the hippocampal neuronal culture model of acquired epilepsy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
7. [CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
8. [Striatal adenosine A2A and cannabinoid CB1 receptors form functional heteromeric complexes that mediate the motor effects of cannabinoids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
9. [Dynamic imaging of cannabinoid receptor 1 vesicular trafficking in cultured astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
10. [Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
11. [Antagonism of the cannabinoid CB-1 receptor protects rat liver against ischaemia-reperfusion injury complicated by endotoxaemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
12. [Expression of type-1 cannabinoid receptor during rat postnatal testicular development: possible involvement in adult leydig cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
13. [Responses to the cannabinoid receptor-1 antagonist, AM251, are more robust with age and with high-fat feeding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
14. [Palatable high-energy diet decreases the expression of cannabinoid type 1 receptor messenger RNA in specific brain regions in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
15. [Integrated cannabinoid CB1 receptor transmission within the amygdala-prefrontal cortical pathway modulates neuronal plasticity and emotional memory encoding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
16. [The CB1 receptor agonist, WIN 55,212-2, dose-dependently disrupts object recognition memory in adult rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
17. [Cannabinoid 1 receptor and interleukin-6 receptor together induce integration of protein kinase and transcription factor signaling to trigger neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
18. [Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
19. [Cannabinoid receptor-mediated antinociception with acetaminophen drug combinations in rats with neuropathic spinal cord injury pain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
20. [Endogenous cannabinoids induce fever through the activation of CB1 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
21. [Effects of the cannabinoid CB1 antagonist rimonabant on hepatic mitochondrial function in rats fed a high-fat diet](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
22. [Two opposite effects of Delta(9)-tetrahydrocannabinol on subthalamic nucleus neuron activity: involvement of GABAergic and glutamatergic neurotransmission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
23. [Central cannabinoid 1 receptor antagonist administration prevents endotoxic hypotension affecting norepinephrine release in the preoptic anterior hypothalamic area](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
24. [Cannabinoids reduce granuloma-associated angiogenesis in rats by controlling transcription and expression of mast cell protease-5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
25. [D2 receptor-mediated inhibition of dopamine release in the rat striatum in vitro is modulated by CB1 receptors: studies using fast cyclic voltammetry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
26. [Effects of rimonabant on the reinstatement of nicotine-conditioned place preference by drug priming in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
27. [Methanandamide attenuates cocaine-induced hyperthermia in rats by a cannabinoid CB1-dopamine D2 receptor mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
28. [Anandamide-induced cell death: dual effects in primary rat decidual cell cultures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
29. [Cannabinoid 1 receptor activation inhibits transient receptor potential vanilloid type 1 receptor-mediated cationic influx into rat cultured primary sensory neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
30. [Sub-chronic administration of AM251, CB1 receptor antagonist, within the nucleus accumbens induced sensitization to morphine in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
31. [CB1 receptor blockade decreases ethanol intake and associated neurochemical changes in fawn-hooded rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
32. [Evidence that MDMA ('ecstasy') increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
33. [Effects of chronic treatment with the CB1 antagonist, rimonabant on the blood pressure, and vascular reactivity of obese Zucker rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
34. [The CB1 antagonist rimonabant decreases insulin hypersecretion in rat pancreatic islets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
35. [Dual effect of anandamide on rat placenta nitric oxide synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
36. [Spatio-temporal expression patterns of anandamide-binding receptors in rat implantation sites: evidence for a role of the endocannabinoid system during the period of placental development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
37. [Age-dependent effects of the cannabinoid CB1 antagonist SR141716A on food intake, body weight change, and pruritus in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
38. [Anandamide improves the impaired nitric oxide-mediated neurogenic relaxation of the corpus cavernosum in diabetic rats: involvement of cannabinoid CB1 and vanilloid VR1 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P20272)
39. ensembl Release 104