# Calpain 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21115584](https://www.wikidata.org/wiki/Q21115584)  
**Source**: https://4ort.xyz/entity/calpain-1-q21115584


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P07384)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
5. [Advanced glycation end‐products induce calpain‐mediated degradation of ezrin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
6. [Calcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
7. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
8. [Calpain-mediated degradation of reversibly oxidized protein-tyrosine phosphatase 1B](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
10. [Calcium-binding properties of human erythrocyte calpain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
11. [Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
12. [Characterization of a functional domain of human calpastatin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
13. [Fyn-mediated phosphorylation of NR2B Tyr-1336 controls calpain-mediated NR2B cleavage in neurons and heterologous systems](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
14. [Molecular mode of action of a covalently inhibiting peptidomimetic on the human calpain protease core](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
15. [Characterization of a functional domain of human calpastatin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
17. [Association of the calpain/calpastatin network with subcellular organelles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
18. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
19. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
20. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
21. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
22. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
23. [Autolysis of human erythrocyte calpain produces two active enzyme forms with different cell localization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
24. [Deimination of human filaggrin-2 promotes its proteolysis by calpain 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
25. [Calpain II colocalizes with detergent-insoluble rafts on human and Jurkat T-cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
26. [Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
27. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
28. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
29. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
30. [The major calpain isozymes are long-lived proteins. Design of an antisense strategy for calpain depletion in cultured cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
31. [The calpain system as a modulator of stress/damage response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
32. [Modulation of the calpain autoproteolysis by calpastatin and phospholipids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
33. [A novel member of the calcium-dependent cysteine protease family](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
34. [Deimination of human filaggrin-2 promotes its proteolysis by calpain 1](http://www.ebi.ac.uk/QuickGO/annotations?protein=P07384&geneProductId=UniProtKB:P07384)
35. [A novel member of the calcium-dependent cysteine protease family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07384)
36. Ensembl Release 99