# Calcium voltage-gated channel subunit alpha1 C

> mammalian protein found in Homo sapiens

**Wikidata**: [Q1499998](https://www.wikidata.org/wiki/Q1499998)  
**Source**: https://4ort.xyz/entity/calcium-voltage-gated-channel-subunit-alpha1-c-q1499998


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13936)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
6. [Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
7. [Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
8. [Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
9. [Molecular coupling of a Ca2+-activated K+ channel to L-type Ca2+ channels via alpha-actinin2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
10. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
11. [Long QT syndrome type 8: novel CACNA1C mutations causing QT prolongation and variant phenotypes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
12. [Effects of methylmercury on human neuronal L-type calcium channels transiently expressed in human embryonic kidney cells (HEK-293)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
13. [Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
14. [Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
15. [Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
16. [Skeletal and cardiac ryanodine receptors bind to the Ca(2+)-sensor region of dihydropyridine receptor alpha(1C) subunit](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
17. [Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
18. [Identification and Functional Characterization of a Novel CACNA1C -Mediated Cardiac Disorder Characterized by Prolonged QT Intervals With Hypertrophic Cardiomyopathy, Congenital Heart Defects, and Sudden Cardiac Death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
19. [Ca2+-binding protein-1 facilitates and forms a postsynaptic complex with Cav1.2 (L-type) Ca2+ channels](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
21. [Skeletal and cardiac ryanodine receptors bind to the Ca(2+)-sensor region of dihydropyridine receptor alpha(1C) subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
23. [Long QT syndrome type 8: novel CACNA1C mutations causing QT prolongation and variant phenotypes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
24. [Effects of methylmercury on human neuronal L-type calcium channels transiently expressed in human embryonic kidney cells (HEK-293)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
25. [Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
26. [Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
27. [A FORM OF TACHYCARDIA CAUSED BY DIGITALIS (PAROXYSMAL AURICULAR TACHYCARDIA WITH BLOCK)](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
28. [A FORM OF TACHYCARDIA CAUSED BY DIGITALIS (PAROXYSMAL AURICULAR TACHYCARDIA WITH BLOCK)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
29. [New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13936&geneProductId=UniProtKB:Q13936)
30. [Severe arrhythmia disorder caused by cardiac L-type calcium channel mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
31. [New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13936)
32. Ensembl Release 99
33. Identifiers.org
34. Transporter Classification database