# Calcium voltage-gated channel subunit alpha1 A

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21104701](https://www.wikidata.org/wiki/Q21104701)  
**Source**: https://4ort.xyz/entity/calcium-voltage-gated-channel-subunit-alpha1-a


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O00555)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
5. [Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
6. [Differential modulation of Ca(v)2.1 channels by calmodulin and Ca2+-binding protein 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
7. [Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
8. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O00555)
9. [Spinocerebellar ataxia type 6 mutation alters P-type calcium channel function](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O00555)
10. [Systematic identification of splice variants in human P/Q-type channel alpha1(2.1) subunits: implications for current density and Ca2+-dependent inactivation](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O00555)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00555&geneProductId=UniProtKB:O00555)
12. [Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O00555)
13. [A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=O00555)
14. [Synthetic Aβ oligomers (Aβ1–42 globulomer) modulate presynaptic calcium currents: Prevention of Aβ-induced synaptic deficits by calcium channel blockers](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
15. [A β‐amyloid oligomer directly modulates P/Q‐type calcium currents inXenopusoocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00555&geneProductId=UniProtKB:O00555)
16. [Spinocerebellar ataxia type 6 mutation alters P-type calcium channel function](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00555&geneProductId=UniProtKB:O00555)
17. [Systematic identification of splice variants in human P/Q-type channel alpha1(2.1) subunits: implications for current density and Ca2+-dependent inactivation](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00555&geneProductId=UniProtKB:O00555)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O00555&geneProductId=UniProtKB:O00555)
19. [Congenital ataxia and hemiplegic migraine with cerebral edema associated with a novel gain of function mutation in the calcium channel CACNA1A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
20. [A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of CaV2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca2+ Influx](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
21. [A β‐amyloid oligomer directly modulates P/Q‐type calcium currents inXenopusoocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
22. [Systematic identification of splice variants in human P/Q-type channel alpha1(2.1) subunits: implications for current density and Ca2+-dependent inactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
23. [Spinocerebellar ataxia type 6 mutation alters P-type calcium channel function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
24. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
25. [C-termini of P/Q-type Ca2+ channel alpha1A subunits translocate to nuclei and promote polyglutamine-mediated toxicity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
26. [Amyloid beta oligomers (A beta(1-42) globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00555)
27. Ensembl Release 99
28. Identifiers.org
29. Transporter Classification database