# Calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

> mammalian protein found in Mus musculus

**Wikidata**: [Q21984376](https://www.wikidata.org/wiki/Q21984376)  
**Source**: https://4ort.xyz/entity/calcium-channel-voltage-dependent-p-q-type-alpha-1a-subunit


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P97445)
3. Q20641742
4. [Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
5. [beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97445&geneProductId=UniProtKB:P97445)
8. [Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97445&geneProductId=UniProtKB:P97445)
9. [Single tottering mutations responsible for the neuropathic phenotype of the P-type calcium channel](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97445&geneProductId=UniProtKB:P97445)
10. [Altered Calcium Channel Currents in Purkinje Cells of the Neurological Mutant Mouseleaner](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97445&geneProductId=UniProtKB:P97445)
11. [Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97445&geneProductId=UniProtKB:P97445)
12. [Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97445&geneProductId=UniProtKB:P97445)
13. [Effects of expression of a mouse brain L-type calcium channel alpha 1 subunit on secretion from bovine adrenal chromaffin cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P97445&geneProductId=UniProtKB:P97445)
14. [Functional compensation of P/Q by N-type channels blocks short-term plasticity at the calyx of Held presynaptic terminal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
15. [Reduced voltage sensitivity of activation of P/Q-type Ca2+ channels is associated with the ataxic mouse mutation rolling Nagoya (tg(rol))](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
16. [Dystonia and cerebellar atrophy in Cacna1a null mice lacking P/Q calcium channel activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
17. [Whole-Cell and Single-Channel Analysis of P-Type Calcium Currents in Cerebellar Purkinje Cells of Leaner Mutant Mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
18. [Altered properties of quantal neurotransmitter release at endplates of mice lacking P/Q-type Ca2+ channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
19. [Cerebellar slice cultures from mice lacking the P/Q calcium channel: electroresponsiveness of Purkinje cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
20. [Characterization of acute somatosensory pain transmission in P/Q‐type Ca2+ channel mutant mice, leaner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
21. [Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
22. [A perforated patch-clamp study of calcium currents and exocytosis in chromaffin cells of wild-type and alpha(1A) knockout mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
23. [Novel Cav2.1 Splice Variants Isolated from Purkinje Cells Do Not Generate P-type Ca2+ Current](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
24. [Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
25. [Single tottering mutations responsible for the neuropathic phenotype of the P-type calcium channel](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
26. [Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
27. [Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
28. [Altered Calcium Channel Currents in Purkinje Cells of the Neurological Mutant Mouseleaner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
29. [Effects of expression of a mouse brain L-type calcium channel alpha 1 subunit on secretion from bovine adrenal chromaffin cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
30. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
31. [Abnormal cortical synaptic transmission in CaV2.1 knockin mice with the S218L missense mutation which causes a severe familial hemiplegic migraine syndrome in humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
32. [Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
33. [The observation of rolling mouse Nagoya (rol), a new neurological mutant, and its maintenance (author's transl)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
34. [Analysis of voltage-gated and synaptic conductances contributing to network excitability defects in the mutant mouse tottering](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
35. [Tottering mouse motor dysfunction is abolished on the Purkinje cell degeneration (pcd) mutant background](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
36. [Abnormal transmitter release at neuromuscular junctions of mice carrying the tottering alpha(1A) Ca(2+) channel mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
37. [Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the alpha1A subunit of P/Q type calcium channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
38. [A burst-dependent hippocampal excitability defect elicited by potassium at the developmental onset of spike-wave seizures in the Tottering mutant](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
39. [Striatal dysfunction in Rolling mouse Nagoya: an electrophysiological study](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
40. [Possible mechanisms underlying hyperexcitability in the epileptic mutant mouse tottering](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
41. [Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
42. [Cerebellar volume decreases in the tottering mouse are specific to the molecular layer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
43. [Morphologic investigation of rolling mouse Nagoya (tg(rol)/tg(rol)) cerebellar Purkinje cells: an ataxic mutant, revisited](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
44. [P/Q-type Ca2+ channel alpha1A regulates synaptic competition on developing cerebellar Purkinje cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
45. [Topological relationship between corticotropin-releasing factor-immunoreactive cerebellar afferents and tyrosine hydroxylase-immunoreactive Purkinje cells in a hereditary ataxic mutant, rolling mouse Nagoya](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
46. [Increased serotonergic innervation of lumbosacral motoneurons of rolling mouse Nagoya in correlation with abnormal hindlimb extension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
47. [Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
48. [Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
49. [Pain sensitivity in mice lacking the Ca(v)2.1alpha1 subunit of P/Q-type Ca2+ channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)
50. [Mutant mouse tottering: selective increase of locus ceruleus axons in a defined single-locus mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P97445)