# Cadherin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21171812](https://www.wikidata.org/wiki/Q21171812)  
**Source**: https://4ort.xyz/entity/cadherin-1-q21171812


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12830&geneProductId=UniProtKB:P12830)
4. [The CD46-Jagged1 interaction is critical for human TH1 immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
5. [Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
6. [Identification of a physiological E2 module for the human anaphase-promoting complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
7. [Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
8. [ASPP2 controls epithelial plasticity and inhibits metastasis through β-catenin-dependent regulation of ZEB1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
9. [Centralspindlin and α-catenin regulate Rho signalling at the epithelial zonula adherens](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
10. [The Tensin-3 protein, including its SH2 domain, is phosphorylated by Src and contributes to tumorigenesis and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
11. [Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
12. [Biosensor-based micro-affinity purification for the proteomic analysis of protein complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
13. [The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
14. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
15. [Hypoxia and cell cycle regulation of the von Hippel-Lindau tumor suppressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
16. [EPLIN mediates linkage of the cadherin catenin complex to F-actin and stabilizes the circumferential actin belt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
17. [FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
18. [Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
19. [Molecular basis of actin reorganization promoted by binding of enterohaemorrhagic Escherichia coli EspB to alpha-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
20. [Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
21. [Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
22. [A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
23. [Rack1 promotes epithelial cell–cell adhesion by regulating E-cadherin endocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
24. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
25. [Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
26. [Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
27. [Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
28. [Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
29. [E-cadherin phosphorylation by protein kinase D1/protein kinase C{mu} is associated with altered cellular aggregation and motility in prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
30. [Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
31. [Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
32. [Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
33. [Plakoglobin, or an 83-kD homologue distinct from beta-catenin, interacts with E-cadherin and N-cadherin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
34. [Armus is a Rac1 effector that inactivates Rab7 and regulates E-cadherin degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
35. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
36. [E-cadherin-dependent transcriptional control of apolipoprotein A-IV gene expression in intestinal epithelial cells: a role for the hepatic nuclear factor 4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
37. [Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
38. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12830&geneProductId=UniProtKB:P12830)
39. [The extracellular architecture of adherens junctions revealed by crystal structures of type I cadherins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
40. [Characterizing the initial encounter complex in cadherin adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
41. [Ideal, catch, and slip bonds in cadherin adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
42. [Intestinal brush border assembly driven by protocadherin-based intermicrovillar adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
43. [Resolving cadherin interactions and binding cooperativity at the single-molecule level](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
44. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
45. [E-cadherin interactome complexity and robustness resolved by quantitative proteomics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
46. [Cadherin and catenin expression in normal human bronchial epithelium and non-small cell lung cancer](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12830&geneProductId=UniProtKB:P12830)
47. [Flotillin microdomains stabilize cadherins at cell-cell junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
48. [GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12830)
49. [Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12830&geneProductId=UniProtKB:P12830)
50. [Flotillin microdomains stabilize cadherins at cell-cell junctions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P12830&geneProductId=UniProtKB:P12830)