# C9orf72, member of C9orf72-SMCR8 complex

> mammalian protein found in Mus musculus

**Wikidata**: [Q28563691](https://www.wikidata.org/wiki/Q28563691)  
**Source**: https://4ort.xyz/entity/c9orf72-member-of-c9orf72-smcr8-complex


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q6DFW0)
3. Q20641742
4. [Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
5. [C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
7. [C9ORF72 expression and cellular localization over mouse development.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
8. [Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
10. [A C9ORF72/SMCR8-containing complex regulates ULK1 and plays a dual role in autophagy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q6DFW0&geneProductId=UniProtKB:Q6DFW0)
12. [C9orf72 is required for proper macrophage and microglial function in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
13. [C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
14. [The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6DFW0)
15. ensembl Release 106