# C-X-C motif chemokine receptor 4

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q57612958](https://www.wikidata.org/wiki/Q57612958)  
**Source**: https://4ort.xyz/entity/c-x-c-motif-chemokine-receptor-4-q57612958


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O08565)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
5. [Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
7. [Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
8. [In vitro model of vasculo-angiogenesis: demonstration that bone marrow derived endothelial progenitor cells form new hybrid capillary blood vessels jointly with gastric endothelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
9. [CXCR-7 receptor promotes SDF-1α-induced migration of bone marrow mesenchymal stem cells in the transient cerebral ischemia/reperfusion rat hippocampus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
10. [Dendrite-selective redistribution of the chemokine receptor CXCR4 following agonist stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
11. [Structural localization and expression of CXCL12 and CXCR4 in rat heart and isolated cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
12. [Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
13. [Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
14. [CXCL12 activation of CXCR4 regulates mucosal host defense through stimulation of epithelial cell migration and promotion of intestinal barrier integrity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
15. [Sprouting of Nervous Fibers and Upregulation of C‐X‐C Chemokine Receptor Type 4 Expression in Hippocampal Formation of Rats with Enhanced Spatial Learning and Memory](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
16. [Tonic activation of CXC chemokine receptor 4 in immature granule cells supports neurogenesis in the adult dentate gyrus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
17. [Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
18. [The effect of CXCL12 on endothelial progenitor cells: potential target for angiogenesis in intracerebral hemorrhage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
19. [Cyclic AMP and tumor necrosis factor-alpha regulate CXCR4 gene expression in Schwann cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
20. [Effects of miR-338 on morphine tolerance by targeting CXCR4 in a rat model of bone cancer pain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
21. [CXCR4 antagonist AMD3100 reverses the neurogenesis promoted by enriched environment and suppresses long-term seizure activity in adult rats of temporal lobe epilepsy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
22. [Human immunodeficiency virus strains differ in their ability to infect CD4+ cells expressing the rat homolog of CXCR-4 (fusin)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
23. [Down-Regulation of CXCL12/CXCR4 Expression Alleviates Ischemia-Reperfusion-Induced Inflammatory Pain via Inhibiting Glial TLR4 Activation in the Spinal Cord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
24. [CD4 dependence of gp120IIIB-CXCR4 interaction is cell-type specific](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
25. [CXCR4 modulates contractility in adult cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
26. [Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
27. [Low intensity pulsed ultrasound enhanced mesenchymal stem cell recruitment through stromal derived factor-1 signaling in fracture healing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
28. [CXCL12 induces migration of oligodendrocyte precursor cells through the CXCR4‑activated MEK/ERK and PI3K/AKT pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O08565)
29. ensembl Release 106