# C-X-C motif chemokine receptor 2

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21113125](https://www.wikidata.org/wiki/Q21113125)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Interleukin_8_receptor,_beta)  
**Source**: https://4ort.xyz/entity/c-x-c-motif-chemokine-receptor-2


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3039531)
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2178579)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL216981)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL191413)
6. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P25025)
7. Q20641742
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
9. [Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
10. [Structure and Functional Expression of a Human Interleukin-8 Receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
11. [HIV-1 matrix protein p17 promotes angiogenesis via chemokine receptors CXCR1 and CXCR2.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
12. [Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
13. [Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
14. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25025&geneProductId=UniProtKB:P25025)
15. [Point mutation causing constitutive signaling of CXCR2 leads to transforming activity similar to Kaposi's sarcoma herpesvirus-G protein-coupled receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
17. [Induction of functional IL-8 receptors by IL-4 and IL-13 in human monocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
18. [Expression and functional activity of the IL-8 receptor type CXCR1 and CXCR2 on human mast cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
19. [Cloning of a cDNA encoding a mouse homolog of the interleukin-8 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
20. [Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25025&geneProductId=UniProtKB:P25025)
21. [Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
22. [The multiple personalities of the chemokine receptor CCR7 in dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
23. [Induction of functional IL-8 receptors by IL-4 and IL-13 in human monocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25025&geneProductId=UniProtKB:P25025)
24. [Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?protein=P25025&geneProductId=UniProtKB:P25025)
25. [Ligand-induced desensitization of the human CXC chemokine receptor-2 is modulated by multiple serine residues in the carboxyl-terminal domain of the receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25025)
26. Ensembl Release 99