C-X-C motif chemokine receptor 2
type: Thing
description: mammalian protein found in Rattus norvegicus
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P35407
additional property: PropertyValue
  property ID: P361
  value: G protein-coupled receptor, rhodopsin-like
additional property: PropertyValue
  property ID: P361
  value: CXC chemokine receptor 2
additional property: PropertyValue
  property ID: P361
  value: membrane protein
additional property: PropertyValue
  property ID: P527
  value: GPCR, rhodopsin-like, 7TM
additional property: PropertyValue
  property ID: P637
  value: NP_058879
additional property: PropertyValue
  property ID: P680
  value: molecular function
additional property: PropertyValue
  property ID: P680
  value: interleukin-8 receptor activity
additional property: PropertyValue
  property ID: P680
  value: G protein-coupled receptor activity
additional property: PropertyValue
  property ID: P681
  value: cellular component
additional property: PropertyValue
  property ID: P681
  value: plasma membrane
additional property: PropertyValue
  property ID: P681
  value: external side of plasma membrane
additional property: PropertyValue
  property ID: P682
  value: acute inflammatory response to antigenic stimulus
additional property: PropertyValue
  property ID: P682
  value: positive regulation of leukocyte chemotaxis
additional property: PropertyValue
  property ID: P682
  value: chemotaxis
additional property: PropertyValue
  property ID: P702
  value: Cxcr2
additional property: PropertyValue
  property ID: P703
  value: brown rat
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000019109
additional property: PropertyValue
  property ID: P705
  value: ENSRNOP00000071417
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 16
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 16
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P35407
    source count: 1
    confidence: 0.2
  P361:
    value: Q7321217
    source count: 1
    confidence: 0.2
    value label: G protein-coupled receptor, rhodopsin-like
  P361:
    value: Q24776433
    source count: 1
    confidence: 0.2
    value label: CXC chemokine receptor 2
  P361:
    value: Q423042
    source count: 1
    confidence: 0.2
    value label: membrane protein
  P361:
    value: Q83162561
    source count: 1
    confidence: 0.2
    value label: GPCR, rhodopsin-like, 7TM, protein family
  P527:
    value: Q24781798
    source count: 1
    confidence: 0.2
    value label: GPCR, rhodopsin-like, 7TM
  P637:
    value: NP_058879
    source count: 1
    confidence: 0.2
  P680:
    value: Q14860489
    source count: 1
    confidence: 0.2
    value label: molecular function
  P680:
    value: Q21113121
    source count: 1
    confidence: 0.2
    value label: interleukin-8 receptor activity
  P680:
    value: Q14859545
    source count: 3
    confidence: 0.6
    value label: G protein-coupled receptor activity
  P680:
    value: Q14864357
    source count: 1
    confidence: 0.2
    value label: chemokine receptor activity
  P680:
    value: Q14865164
    source count: 1
    confidence: 0.2
    value label: C-C chemokine receptor activity
  P681:
    value: Q5058355
    source count: 1
    confidence: 0.2
    value label: cellular component
  P681:
    value: Q29548
    source count: 1
    confidence: 0.2
    value label: plasma membrane
  P681:
    value: Q14633850
    source count: 1
    confidence: 0.2
    value label: external side of plasma membrane
  P681:
    value: Q189094
    source count: 1
    confidence: 0.2
    value label: cell surface
  P681:
    value: Q14349455
    source count: 2
    confidence: 0.4
    value label: membrane
  P682:
    value: Q14905642
    source count: 1
    confidence: 0.2
    value label: acute inflammatory response to antigenic stimulus
  P682:
    value: Q14864635
    source count: 1
    confidence: 0.2
    value label: positive regulation of leukocyte chemotaxis
  P682:
    value: Q658145
    source count: 4
    confidence: 0.8
    value label: chemotaxis
  P682:
    value: Q1612119
    source count: 1
    confidence: 0.2
    value label: immune response
  P682:
    value: Q14864077
    source count: 1
    confidence: 0.2
    value label: cellular defense response
  P702:
    value: Q24407409
    source count: 1
    confidence: 0.2
    value label: Cxcr2
  P703:
    value: Q184224
    source count: 1
    confidence: 0.2
    value label: brown rat

value: ENSRNOP00000019109
source count: 1
confidence: 0.2

value: ENSRNOP00000071417
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-02-14

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-02-14

source: Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect
stated in qid: Q28573767
retrieved: 2019-02-14

source: CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration
stated in qid: Q28581476
retrieved: 2019-02-14

source: Identification of a common receptor for three types of rat cytokine-induced neutrophil chemoattractants (CINCs)
stated in qid: Q28566046
retrieved: 2019-02-14

source: Electronegative low-density lipoprotein induces cardiomyocyte apoptosis indirectly through endothelial cell-released chemokines
stated in qid: Q28574041
retrieved: 2019-02-14

source: Alpha-chemokines regulate proliferation, neurogenesis, and dopaminergic differentiation of ventral midbrain precursors and neurospheres
stated in qid: Q28568981
retrieved: 2019-02-14

source: Virus-Infected Alveolar Epithelial Cells Direct Neutrophil Chemotaxis and Inhibit Their Apoptosis
stated in qid: Q28575244
retrieved: 2019-02-14

source: ELR+-CXC chemokines and their receptors in early metanephric development
stated in qid: Q28571457
retrieved: 2019-02-14

source: A role for a CXCR2/phosphatidylinositol 3-kinase gamma signaling axis in acute and chronic vascular permeability.
stated in qid: Q28566820
retrieved: 2019-02-14

source: The angiogenic response of the aorta to injury and inflammatory cytokines requires macrophages
stated in qid: Q28579543
retrieved: 2019-02-14

source: Rho-Kinase Inhibitor Prevents Bleomycin-Induced Injury in Neonatal Rats Independent of Effects on Lung Inflammation
stated in qid: Q28570784
retrieved: 2019-02-14

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2021-11-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2021-09-07

source: ensembl Release 104
stated in qid: Q106833387

wikidata id: Q28560434
domain: protein
level: standard
html url: https://4ort.xyz/entity/c-x-c-motif-chemokine-receptor-2-q28560434
markdown url: https://4ort.xyz/entity/c-x-c-motif-chemokine-receptor-2-q28560434.md
facts url summary: https://4ort.xyz/entity/c-x-c-motif-chemokine-receptor-2-q28560434/facts.json
facts url standard: https://4ort.xyz/entity/c-x-c-motif-chemokine-receptor-2-q28560434/facts.json
facts url full: https://4ort.xyz/entity/c-x-c-motif-chemokine-receptor-2-q28560434/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-09T17:46:38.726312Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:27:14.058956+00:00Z