# C-X-C motif chemokine ligand 12

> mammalian protein found in Homo sapiens

**Wikidata**: [Q408598](https://www.wikidata.org/wiki/Q408598)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Stromal_cell-derived_factor_1)  
**Source**: https://4ort.xyz/entity/c-x-c-motif-chemokine-ligand-12


## References

1. UniProt
2. Q20641742
3. Freebase Data Dumps. 2013
4. [Ubiquitination of CXCR7 controls receptor trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
6. [An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
7. [Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
9. [CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
10. [The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
11. [Roles of CD4 and coreceptors in binding, endocytosis, and proteolysis of gp120 envelope glycoproteins derived from human immunodeficiency virus type 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
12. [Inhibition of tyrosine kinase activation blocks the down-regulation of CXC chemokine receptor 4 by HIV-1 gp120 in CD4+ T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
13. [Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
14. [Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
15. [An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
16. [Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
17. [WNK1 kinase balances T cell adhesion versus migration in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
18. [CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
20. [The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
21. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
22. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
23. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
24. [Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
25. [The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
26. [Monocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
27. [A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
28. [The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
29. [Human galectin-3 is a novel chemoattractant for monocytes and macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
30. [Specific activation of leukocyte beta2 integrins lymphocyte function-associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the alpha subunit cytoplasmic domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
31. [Active movement of T cells away from a chemokine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
32. [Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
33. [CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
34. [Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
35. [Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
36. [Crystal structures of human alpha-defensins HNP4, HD5, and HD6](http://www.ebi.ac.uk/QuickGO/annotations?protein=P48061&geneProductId=UniProtKB:P48061)
37. [Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48061)
38. Ensembl Release 99
39. Identifiers.org
40. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)