# C-X-C motif chemokine ligand 10

> mammalian protein found in Homo sapiens

**Wikidata**: [Q986112](https://www.wikidata.org/wiki/Q986112)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/CXCL10)  
**Source**: https://4ort.xyz/entity/c-x-c-motif-chemokine-ligand-10


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P02778)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
6. [Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
7. [An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
8. [CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778)
9. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778)
10. [An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778)
11. [Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
12. [Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
13. [Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
14. [CXCR3 expression and activation of eosinophils: role of IFN-gamma-inducible protein-10 and monokine induced by IFN-gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
15. [Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
17. [Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabeta+ CD8+ single-positive T cells, [...]](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
18. [Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
19. [IP-10 blocks vascular endothelial growth factor-induced endothelial cell motility and tube formation via inhibition of calpain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
20. [Citrullination of CXCL10 and CXCL11 by peptidylarginine deiminase: a naturally occurring posttranslational modification of chemokines and new dimension of immunoregulation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778)
21. [Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
22. [Interferon-inducible protein-10 involves vascular smooth muscle cell migration, proliferation, and inflammatory response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
23. [Human interferon-inducible protein-10 induces mononuclear cell infiltration in mice and promotes the migration of human T lymphocytes into the peripheral tissues and human peripheral blood lymphocytes-SCID mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
24. [IP-10 induces dissociation of newly formed blood vessels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
25. [SASH1 Is a Scaffold Molecule in Endothelial TLR4 Signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778)
26. [CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
27. [Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P02778&geneProductId=UniProtKB:P02778)
28. [SASH1 Is a Scaffold Molecule in Endothelial TLR4 Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
29. [Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
30. [CXCL10 contributes to p38-mediated apoptosis in primary T lymphocytes in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02778)
31. Ensembl Release 99
32. UMLS 2023
33. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)