# C-C motif chemokine ligand 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q5009623](https://www.wikidata.org/wiki/Q5009623)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/CCL3)  
**Source**: https://4ort.xyz/entity/c-c-motif-chemokine-ligand-3


## References

1. UniProt
2. Q20641742
3. [Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
5. [Lipopolysaccharide inhibits HIV-1 infection of monocyte- derived macrophages through direct and sustained down-regulation of CC chemokine receptor 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
6. [Cloning and functional expression of CC CKR5, a human monocyte CC chemokine receptor selective for MIP-1(alpha), MIP-1(beta), and RANTES](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
8. [Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
9. [Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
10. [Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
11. [A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
12. [Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
13. [A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
14. [Zinc finger protein tristetraprolin interacts with CCL3 mRNA and regulates tissue inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
15. [Structures of Orf Virus Chemokine Binding Protein in Complex with Host Chemokines Reveal Clues to Broad Binding Specificity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
16. [Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
17. [Human LZIP binds to CCR1 and differentially affects the chemotactic activities of CCR1-dependent chemokines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
18. [Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
19. [Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
21. [Distinct modes of molecular regulation of CCL3 induced calcium flux in monocytic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
22. [Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
23. [CCL3 correlates with the number of mood disturbances and personality changes in patients with Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
24. [A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
25. [CCL3 correlates with the number of mood disturbances and personality changes in patients with Alzheimer's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
26. [p38 MAPK phosphorylation and NF-kappa B activation in human crescentic glomerulonephritis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
27. [Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
28. [Cutaneous injection of human subjects with macrophage inflammatory protein-1 alpha induces significant recruitment of neutrophils and monocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
29. [Lymphocyte-derived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
30. [Human galectin-3 is a novel chemoattractant for monocytes and macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
31. [Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
32. [Lipopolysaccharide inhibits HIV-1 infection of monocyte- derived macrophages through direct and sustained down-regulation of CC chemokine receptor 5](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10147&geneProductId=UniProtKB:P10147)
33. [In vitro correlates of HIV-2-mediated HIV-1 protection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
34. [Lymphocyte-derived cytokines induce sequential expression of monocyte- and T cell-specific chemokines in human mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
35. [TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10147)
36. Ensembl Release 99
37. Identifiers.org
38. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)