# Building efficient comparative effectiveness trials through adaptive designs, utility functions, and accrual rate optimization: finding the sweet spot

> Research article (Statistics in Medicine, 2015) · cited 25× · AI/ML

**Wikidata**: [openalex:W1953260577](https://www.wikidata.org/wiki/openalex:W1953260577)  
**Source**: https://4ort.xyz/entity/building-efficient-comparative-effectiveness-trials-through-adaptive-designs-utility-functions-and-accrual-rate-optimiza